Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Name: Sulfamethazine sodium, 1981-58-4, Name is Sulfamethazine sodium, molecular formula is C12H13N4NaO2S, belongs to pyrimidines compound. In a document, author is Zhang, Yongjie, introduce the new discover.
Pyrazolo[1,5-a]pyrimidine based Trk inhibitors: Design, synthesis, biological activity evaluation
Tropomyosin receptor kinases (Trks), a transmembrane receptor tyrosine kinases, have attracted more and more attention as a drug target. Here we reported the structure-based synthesis and biological evaluation of novel pyrazolo[1,5-a]pyrimidine derivatives as Trk inhibitors, which exhibited potent Trk inhibitory activities. Particularly, compounds 8a, 8f, 9a, 9b and 9f (IC50 < 5 nM) showed significant inhibitory potency against Trk. A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 1981-58-4. Name: Sulfamethazine sodium.
Reference:
Pyrimidine | C4H4N2 – PubChem,
,Pyrimidine – Wikipedia