Electric Literature of 947533-45-1, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 947533-45-1, Name is 2-bromo-5-fluoropyrimidine, SMILES is FC1=CN=C(Br)N=C1, belongs to pyrimidines compound. In a article, author is Vyshtakalyuk, A. B., introduce new discover of the category.
Double Pyrimidine Derivatives: Synthesis and Primary Assessment of Hepatoprotective Properties In Vitro
Double derivatives of the drug Xymedon (1,2-dihydro-4,6-dimethyl-1-N-(hydroxyethyl)pyrimidone-2), hereafter referred to as pyrimidine (I), in which the pyrimidine (I) molecules are joined by an alkyl(xylylenyl)dionate bridge have been synthesized. Primary data on the hepatoprotective activity of five double pyrimidine (I) derivatives with different numbers of methylene groups and a meta-xylylene fragment in the ester bridge have been obtained on normal human hepatocytes of the Chang Liver cell line. The cytotoxicity and the cytoprotective properties of the new compounds against the background of exposure to d-galactosamine at a concentration of 150 mmol/L have been determined, their effect on the cell cycle compared with that of the initial pyrimidine (I) has been studied, and the dependence of the biological properties of the derivatives on their structure has been established.
Electric Literature of 947533-45-1, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 947533-45-1 is helpful to your research.
Reference:
Pyrimidine | C4H4N2 – PubChem,
,Pyrimidine – Wikipedia