Some scientific research about 2-(Methylthio)pyrimidine-4,6-diamine

The synthetic route of 1005-39-6 has been constantly updated, and we look forward to future research findings.

Adding a certain compound to certain chemical reactions, such as: 1005-39-6, 2-(Methylthio)pyrimidine-4,6-diamine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Product Details of 1005-39-6, blongs to pyrimidines compound. Product Details of 1005-39-6

740 mg (2.70 mmol) of ethyl 2-(4-cyano-2-methoxybenzylidene)-3-oxobutanoate and 422 mg (2.70 mmol) of 2-(methylthio)pyrimidine-4,6-diamine are dissolved in 5 ml of isopropanol and heated under reflux under argon for 12 h. The mixture is filtered and the remaining solid is washed with isopropanol. 395 mg (35% of theory) of the title compound are obtained as a white solid. LC-MS (method 1): Rt=2.06 min; [M+H]+=412 1H-NMR (400 MHz, DMSO-d6): delta=1.02 (t, 3H), 2.33 (s, 3H), 2.36 (s, 3H), 3.86 (q, 2H), 3.90 (s, 3H), 5.19 (s, 1H), 6.27 (s, 2H), 7.36 (s, 2H), 7.47 (s, 1H), 7.92 (dd, 1H), 9.58 (s, 1H).

The synthetic route of 1005-39-6 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; BAYER HEALTHCARE AG; US2010/35902; (2010); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

New downstream synthetic route of 2-(Methylthio)pyrimidine-4,6-diamine

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 1005-39-6, 2-(Methylthio)pyrimidine-4,6-diamine.

Electric Literature of 1005-39-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1005-39-6, name is 2-(Methylthio)pyrimidine-4,6-diamine. This compound has unique chemical properties. The synthetic route is as follows.

Step 1) Synthesis of 4,5,6-triamino-2-methylthiopyrimidine To a solution of 245g of 4,6-diamino-2-methylthiopyrimidine dissolved in 800 ml of acetic acid was added 250 ml of water. The reaction solution was cooled to 10C and thereto was added a solution of 119g of NaNO2 dissolved in 250 ml of water while maintaining the temperature at 10C. The reaction mixture was stirred at room temperature for 2 hours, filtered and dried to obtain 4,6-diamino-5-nitroso-2-methylthiopyrimidine, which was then dissolved in 1l of water.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 1005-39-6, 2-(Methylthio)pyrimidine-4,6-diamine.

Reference:
Patent; LUCKY LTD.; EP584797; (1994); A2;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia