Category: 109-12-6

The pyrimidine ring system has wide occurrence in nature as substituted and ring fused compounds and derivatives, including the nucleotides cytosine, thymine and uracil, thiamine (vitamin B1) and alloxan. 109-12-6, formula is C4H5N3, Name is Pyrimidin-2-amine. It is also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. Category: pyrimidines.

Xuan, G. S.;Zhan, J. H.;Zhang, A. M.;Li, W.;Zheng, K. research published 《 Inhibition of carbonic anhydrase II by sulfonamide derivatives》, the research content is summarized as follows. A series of sulfonamide derivatives I [R = NH₂, ethoxycarbonylazanyl, (pyrimidin-2-yl)aminyl, 3-methyl-5-phenyl-1H-pyrazol-1-yl, etc.; R¹ = H, C(O)CH₃] were synthesized, and the enzyme inhibitory activity of the synthesized compounds I on carbonic anhydrase II was evaluated. Through mol. docking studies, it was found that compounds I [R = NHNH₂, R¹ = C(O)CH₃; R = (pyrimidin-2-yl)aminyl, R¹ = C(O)CH₃ (II); R = acetamidyl, R¹ = C(O)CH₃; R = ethoxycarbonylazanyl, R¹ = C(O)CH₃ (III); R = 3,5-dimethyl-1H-pyrazol-1-yl, R¹ = H (IV)] have a strong binding affinity to carbonic anhydrase II. The IC₅₀ values of the four compounds II, III, IV and I (R = 3-methyl-5-phenyl-1H-pyrazol-1-yl; R¹ = H) were lower than that of the pos. control drug acetazolamide. What’s more, the compounds had a high inhibitory activity for A549 lung cancer cell growth, among them, II and IV could inhibit both carbonic anhydrase II and lung cancer cell proliferation.

109-12-6, 2-Aminopyrimidine is a useful research compound. Its molecular formula is C4H5N3 and its molecular weight is 95.1 g/mol. The purity is usually 95%.
2-Aminopyrimidine is an organic compound that belongs to the group of pyridines. It has been shown to have antimicrobial, antitumor, and antiviral properties. 2-Aminopyrimidine has been used as a fungicide and herbicide in horticulture and agriculture, respectively. The molecular geometry of this molecule is octahedral with coordination geometry C2v. This chemical binds to the BCR-ABL kinase receptor and inhibits its activity by competitive inhibition of ATP binding. 2-Aminopyrimidine has been shown to have a hematologic response in vivo models and in vitro assays. It also has anti-inflammatory effects when it is taken orally or applied topically., Category: pyrimidines

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Pyrimidine is a nitrogenous base similar to benzene (a six-membered ring) and includes cytosine, thymine, and uracil as bases used for DNA or RNA. 109-12-6, formula is C4H5N3, Name is Pyrimidin-2-amine. Pyrimidine also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. COA of Formula: C4H5N3.

Yagmur, Hatice Karaer;Kaya, Ismet;Aydin, Haluk research published 《 Synthesis, characterization, thermal and electrochemical features of poly(phenoxy-imine)s containing pyridine and pyrimidine units》, the research content is summarized as follows. Poly(4-hydroxybenzaldehyde) was prepared by via the oxidative polymerization process in an aqueous alk. medium by H₂O₂ as an oxidant. Then, poly(phenoxy-imine)s were synthesized from the condensation reactions of poly(4-hydroxybenzaldehyde) (P-4HBA) with several amines including pyridine and pyrimidine groups. The structures and characterizations of compounds were made by virtue of FT-IR, NMR, UV-Vis spectroscopy, GPC, TG, DSC, CV, SEM and fluorescence (FL) analyses. The conductivities of poly(phenoxy-imine)s were determined with electrometer by four-point probe technique. The conductivity values of poly(phenoxy-imine)s were increased to be connect with doped factor of iodine. Moreover, the elec. conductivity of the poly(phenoxy-imine)s was also measured and defined which they had semi-conductive features. Fluorescence properties of poly(phenoxy-imine)s and P-4HBA were measured out in DMF solutions to define the optimum concentrations in order to acquire the maximal FL intensities. Average mol. weight of the polymers in number (M_n), and in weight (M_w), and polydispersity index (PDI) values of poly(phenoxy-imine)s and P-4HBA were found from GPC anal. The M_n, M_w and PDI values of P-4HBA were found to be 9900 Da (M_n), 11,300 Da (M_w) and 1.14, resp. The electrochem. energy gap (E’_g) and optical band gap (E₂) values of poly(phenoxy-imine)s were determined from cyclic voltammetry (CV) and UV-Vis measurements, resp.

COA of Formula: C4H5N3, 2-Aminopyrimidine is a useful research compound. Its molecular formula is C4H5N3 and its molecular weight is 95.1 g/mol. The purity is usually 95%.
2-Aminopyrimidine is an organic compound that belongs to the group of pyridines. It has been shown to have antimicrobial, antitumor, and antiviral properties. 2-Aminopyrimidine has been used as a fungicide and herbicide in horticulture and agriculture, respectively. The molecular geometry of this molecule is octahedral with coordination geometry C2v. This chemical binds to the BCR-ABL kinase receptor and inhibits its activity by competitive inhibition of ATP binding. 2-Aminopyrimidine has been shown to have a hematologic response in vivo models and in vitro assays. It also has anti-inflammatory effects when it is taken orally or applied topically., 109-12-6.

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Pyrimidine is a nitrogenous base similar to benzene (a six-membered ring) and includes cytosine, thymine, and uracil as bases used for DNA or RNA. 109-12-6, formula is C4H5N3, Name is Pyrimidin-2-amine. Pyrimidine also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. Name: Pyrimidin-2-amine.

Yang, Haiping;Zhang, Ruifeng;Li, Zhong;Maienfisch, Peter;Xu, Xiaoyong research published 《 Design, synthesis and nematicidal activitives of trifluorobutene amide derivatives against Meloidogyne incognita》, the research content is summarized as follows. Plant parasitic nematodes have always been a pressing problem in the field of plant protection. Well-established chem. nematicides, especially organophosphorus and carbamates are the most used products for nematode control worldwide. Due to long-term overuse, they have developed serious resistance and new innovative solutions are urgently required. In this study, thirty-one novel trifluorobutene amide derivatives were designed and synthesized, and their nematicidal activities were determined Three different synthetic methods have been developed for the final amidation reaction enabling the successfully syntheses of the target compounds independently from the nucleophilicities of the substrate amino group. Most target compounds showed good nematicidal activity in our in vitro test. Among all the compounds, compounds I and II exhibited excellent nematicidal activity against Meloidogyne incognita, their LC₅₀ values are 2.02 mg L^-1 and 0.76 mg L^-1, resp. In particular, compound II has found to be almost as active as the com. nematicide fluensulfone. Furthermore, most compounds gave full control (100% inhibition) of M. incognita at 40 mg L^-1 in the in vivo tests in sandy soil, the best compounds were further investigated for in vivo activity in matrix soil. Among the compound tested, compound I showed excellent in vivo nematicidal activity. At a concentration of 5 mg L^-1 still 56% inhibition was observed The results of our study indicate that compound I possesses excellent in vitro and in vivo nematicidal activity, and can be considered as promising lead mol. for further modification.

Name: Pyrimidin-2-amine, 2-Aminopyrimidine is a useful research compound. Its molecular formula is C4H5N3 and its molecular weight is 95.1 g/mol. The purity is usually 95%.
2-Aminopyrimidine is an organic compound that belongs to the group of pyridines. It has been shown to have antimicrobial, antitumor, and antiviral properties. 2-Aminopyrimidine has been used as a fungicide and herbicide in horticulture and agriculture, respectively. The molecular geometry of this molecule is octahedral with coordination geometry C2v. This chemical binds to the BCR-ABL kinase receptor and inhibits its activity by competitive inhibition of ATP binding. 2-Aminopyrimidine has been shown to have a hematologic response in vivo models and in vitro assays. It also has anti-inflammatory effects when it is taken orally or applied topically., 109-12-6.

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine. 109-12-6, formula is C4H5N3, Name is Pyrimidin-2-amine. In nucleic acids, three types of nucleobases are pyrimidine derivatives: cytosine (C), thymine (T), and uracil (U). Application In Synthesis of 109-12-6.

Weig, Alexander W.;Barlock, Samantha L.;O’Connor, Patrick M.;Marciano, Orry M.;Smith, Richard;Ernst, Robert K.;Melander, Roberta J.;Melander, Christian research published 《 A scaffold hopping strategy to generate new aryl-2-amino pyrimidine MRSA biofilm inhibitors》, the research content is summarized as follows. Infections that stem from bacterial biofilms are difficult to eradicate. Within a biofilm state, bacteria are upwards of 1000-fold more resistant to conventional antibiotics, necessitating the development of alternative approaches to treat biofilm-based infections. One such approach is the development of small mol. adjuvants that can inhibit/disrupt bacterial biofilms. When such mols. are paired with conventional antibiotics, these dual treatments present a combination approach to eradicate biofilm-based infections. Previously, we have demonstrated that small mols. containing either a 2-amino pyrimidine (2-AP) or a 2-aminoimidazole (2-AI) heterocycle are potent anti-biofilm agents. Herein, we now report a scaffold hopping strategy to generate new aryl 2-AP analogs that inhibit biofilm formation by methicillin-resistant Staphylococcus aureus (MRSA). These mols. also suppress colistin resistance in colistin resistant Klebsiella pneumoniae, lowering the min. inhibitory concentration (MIC) by 32-fold.

Application In Synthesis of 109-12-6, 2-Aminopyrimidine is a useful research compound. Its molecular formula is C4H5N3 and its molecular weight is 95.1 g/mol. The purity is usually 95%.
2-Aminopyrimidine is an organic compound that belongs to the group of pyridines. It has been shown to have antimicrobial, antitumor, and antiviral properties. 2-Aminopyrimidine has been used as a fungicide and herbicide in horticulture and agriculture, respectively. The molecular geometry of this molecule is octahedral with coordination geometry C2v. This chemical binds to the BCR-ABL kinase receptor and inhibits its activity by competitive inhibition of ATP binding. 2-Aminopyrimidine has been shown to have a hematologic response in vivo models and in vitro assays. It also has anti-inflammatory effects when it is taken orally or applied topically., 109-12-6.

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine. 109-12-6, formula is C4H5N3, Name is Pyrimidin-2-amine. In nucleic acids, three types of nucleobases are pyrimidine derivatives: cytosine (C), thymine (T), and uracil (U). Application of C4H5N3.

Wieczorkiewicz, Pawel A.;Szatylowicz, Halina;Krygowski, Tadeusz M. research published 《 Energetic and Geometric Characteristics of the Substituents: Part 2: The Case of NO₂, Cl, and NH₂ Groups in Their Mono-Substituted Derivatives of Simple Nitrogen Heterocycles》, the research content is summarized as follows. Variously substituted N-heterocyclic compounds are widespread across bio- and medicinal chem. The work aims to computationally evaluate the influence of the type of N-heterocyclic compound and the substitution position on the properties of three model substituents: NO₂, Cl, and NH₂. For this reason, the energetic descriptor of global substituent effect (E_rel), geometry of substituents, and electronic descriptors (cSAR, pEDA, sEDA) are considered, and interdependences between these characteristics are discussed. Furthermore, the existence of an endocyclic N atom may induce proximity effects specific for a given substituent. Therefore, various quantum chem. methods are used to assess them: the quantum theory of atoms in mols. (QTAIM), anal. of non-covalent interactions using reduced d. gradient (RDG) function, and electrostatic potential maps (ESP). The study shows that the energetic effect associated with the substitution is highly dependent on the number and position of N atoms in the heterocyclic ring. Moreover, this effect due to interaction with more than one endo N atom (e.g., in pyrimidines) can be assessed with reasonable accuracy by adding the effects calculated for interactions with one endo N atom in substituted pyridines. Finally, all possible cases of proximity interactions for the NO₂, Cl, and NH₂ groups are thoroughly discussed.

Application of C4H5N3, 2-Aminopyrimidine is a useful research compound. Its molecular formula is C4H5N3 and its molecular weight is 95.1 g/mol. The purity is usually 95%.
2-Aminopyrimidine is an organic compound that belongs to the group of pyridines. It has been shown to have antimicrobial, antitumor, and antiviral properties. 2-Aminopyrimidine has been used as a fungicide and herbicide in horticulture and agriculture, respectively. The molecular geometry of this molecule is octahedral with coordination geometry C2v. This chemical binds to the BCR-ABL kinase receptor and inhibits its activity by competitive inhibition of ATP binding. 2-Aminopyrimidine has been shown to have a hematologic response in vivo models and in vitro assays. It also has anti-inflammatory effects when it is taken orally or applied topically., 109-12-6.

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

The systematic study of pyrimidines began in 1884 with Pinner, who synthesized derivatives by condensing ethyl acetoacetate with amidines. Pinner first proposed the name “pyrimidin” in 1885. 109-12-6, formula is C4H5N3, Name is Pyrimidin-2-amine. The parent compound was first prepared by Gabriel and Colman in 1900, by conversion of barbituric acid to 2,4,6-trichloropyrimidine followed by reduction using zinc dust in hot water. Formula: C4H5N3.

Wu, Chongyang;Ying, Tao;Yang, Xinjie;Su, Weike;Dushkin, Alexandr V.;Yu, Jingbo research published 《 Mechanochemical Magnesium-Mediated Minisci C-H Alkylation of Pyrimidines with Alkyl Bromides and Chlorides》, the research content is summarized as follows. A novel method to synthesize 4-alkylpyrimidines by the mechanochem. magnesium-mediated Minisci reaction of pyrimidine derivatives and alkyl halides was reported. The reaction process operated with a broad substrate scope and excellent regioselectivity under mild conditions with no requirement of transition-metal catalysts, solvents, and inert gas protection. The practicality of this protocol was demonstrated by the up-scale synthesis, mechanochem. product derivatization and preparation of the antimalarial drug pyrimethamine.

Formula: C4H5N3, 2-Aminopyrimidine is a useful research compound. Its molecular formula is C4H5N3 and its molecular weight is 95.1 g/mol. The purity is usually 95%.
2-Aminopyrimidine is an organic compound that belongs to the group of pyridines. It has been shown to have antimicrobial, antitumor, and antiviral properties. 2-Aminopyrimidine has been used as a fungicide and herbicide in horticulture and agriculture, respectively. The molecular geometry of this molecule is octahedral with coordination geometry C2v. This chemical binds to the BCR-ABL kinase receptor and inhibits its activity by competitive inhibition of ATP binding. 2-Aminopyrimidine has been shown to have a hematologic response in vivo models and in vitro assays. It also has anti-inflammatory effects when it is taken orally or applied topically., 109-12-6.

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

The nomenclature of pyrimidines is straightforward. However, like other heterocyclics, tautomeric hydroxyl groups yield complications since they exist primarily in the cyclic amide form. 109-12-6, formula is C4H5N3, Name is Pyrimidin-2-amine. For example, 2-hydroxypyrimidine is more properly named 2-pyrimidone. A partial list of trivial names of various pyrimidines exists. Electric Literature of 109-12-6.

Xiang, Xiaofan;Wu, Laiyan;Zhu, Junjiang;Li, Jiazhou;Liao, Xi;Huang, Hongcheng;Fan, Jiajie;Lv, Kangle research published 《 Photocatalytic degradation of sulfadiazine in suspensions of TiO₂ nanosheets with exposed (001) facets》, the research content is summarized as follows. Antibiotics such as sulfonamides are widely used in agriculture as growth promoters and medicine in treatment of infectious diseases. However, the release of these antibiotics has caused serious environmental problems. In this paper, photocatalytic oxidation technol. was used to degrade sulfadiazine (SDZ), one of the typical sulfonamides antibiotics, in UV illuminated TiO₂ suspensions. It was found that TiO₂ nanosheets (TiO₂-NSs) with exposed (001) facets exhibit much higher photoreactivity towards SDZ degradation compared to TiO₂ nanoparticles (TiO₂-NPs) with a rate constant increases from 0.017 min^-1 to 0.035 min^-1, improving by a factor of 2.1. Under the attacking of reactive oxygen species (ROSs) such as superoxide radicals (·Ousc2) and hydroxyl radicals (·OH), SDZ was steady degraded on the surface of TiO₂-NSs. Based on the identification of the produced intermediates by LC-MS/MS, possible degradation pathways of SDZ, which include desulfonation, oxidation and cleavage, were put forwards. After UV irradiation for 4 h, nearly 90% of the total organic carbon (TOC) can be removed in suspensions of TiO₂-NSs, indicating the mineralization of SDZ. TiO₂-NSs also exhibits excellent stability in photocatalytic degradation of SDZ in wide range of pH. Even after recycling used for 7 times, more than 91.3% of the SDZ can be efficiently removed, indicating that they are promising to be practically used in treatment of wastewater containing antibiotics.

109-12-6, 2-Aminopyrimidine is a useful research compound. Its molecular formula is C4H5N3 and its molecular weight is 95.1 g/mol. The purity is usually 95%.
2-Aminopyrimidine is an organic compound that belongs to the group of pyridines. It has been shown to have antimicrobial, antitumor, and antiviral properties. 2-Aminopyrimidine has been used as a fungicide and herbicide in horticulture and agriculture, respectively. The molecular geometry of this molecule is octahedral with coordination geometry C2v. This chemical binds to the BCR-ABL kinase receptor and inhibits its activity by competitive inhibition of ATP binding. 2-Aminopyrimidine has been shown to have a hematologic response in vivo models and in vitro assays. It also has anti-inflammatory effects when it is taken orally or applied topically., Electric Literature of 109-12-6

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine. 109-12-6, formula is C4H5N3, Name is Pyrimidin-2-amine. In nucleic acids, three types of nucleobases are pyrimidine derivatives: cytosine (C), thymine (T), and uracil (U). Quality Control of 109-12-6.

Wang, Chang-An;Rahman, Mahbubur Md.;Bisz, Elwira;Dziuk, Blazej;Szostak, Roman;Szostak, Michal research published 《 Palladium-NHC (NHC = N-heterocyclic Carbene)-Catalyzed Suzuki-Miyaura Cross-Coupling of Alkyl Amides》, the research content is summarized as follows. The Pd-catalyzed Suzuki-Miyaura cross-coupling of aliphatic amides I (R = t-Bu, Cy, nonyl, etc.) was reported. Although tremendous advances have been made in the cross-coupling of aromatic amide I (R = Ph), C-C bond formation from aliphatic amides I by selective N-C(O) cleavage has remained a major challenge. This longstanding problem in Pd catalysis has been addressed herein by a combination of (1) the discovery of N,N-pym/Boc amides I as a class of readily accessible amide-based reagents for cross-coupling and (2) steric tuning of well-defined Pd(II)-NHC catalysts for cross-coupling. The methodol. is effective for the cross-coupling of an array of 3°, 2°, and 1° aliphatic amide derivatives I. The catalyst system is user-friendly, since the catalysts are readily available and air- and bench-stable. Mechanistic studies strongly support an amide bond twist and external n_N → π*_C=O/Ar delocalization as a unified enabling feature of N,N-pym/Boc amides I in selective N-C(O) bond activation. The method provides a rare example of Pd-NHC-catalyzed cross-coupling of aliphatic acyl amide electrophiles I.

109-12-6, 2-Aminopyrimidine is a useful research compound. Its molecular formula is C4H5N3 and its molecular weight is 95.1 g/mol. The purity is usually 95%.
2-Aminopyrimidine is an organic compound that belongs to the group of pyridines. It has been shown to have antimicrobial, antitumor, and antiviral properties. 2-Aminopyrimidine has been used as a fungicide and herbicide in horticulture and agriculture, respectively. The molecular geometry of this molecule is octahedral with coordination geometry C2v. This chemical binds to the BCR-ABL kinase receptor and inhibits its activity by competitive inhibition of ATP binding. 2-Aminopyrimidine has been shown to have a hematologic response in vivo models and in vitro assays. It also has anti-inflammatory effects when it is taken orally or applied topically., Quality Control of 109-12-6

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

The pyrimidine ring system has wide occurrence in nature as substituted and ring fused compounds and derivatives, 109-12-6, formula is C4H5N3, Name is Pyrimidin-2-amine. including the nucleotides cytosine, thymine and uracil, thiamine (vitamin B1) and alloxan. Product Details of C4H5N3.

Wang, Xinran;Zhang, Cai;Zhang, Xiangyu;Wang, Jiming;Zhao, Liyu;Zhao, Dongmei;Cheng, Maosheng research published 《 Design, synthesis and biological evaluation of 2-aminopyrimidine-based LSD1 inhibitors》, the research content is summarized as follows. AZD9291, with excellent pharmaceutical properties, has been reported to have certain LSD1 inhibitory activity. Therefore, we carried out structural optimization based on the AZD9291 skeleton to increase the LSD1 inhibitory potential of the compound Then, a series of 2-aminopyrimidine derivatives were designed and synthesized as LSD1 inhibitors, and their structure-activity relationships were studied. The most promising compound, X43, with an IC₅₀ of 0.89 μM showed remarkable LSD1 selectivity not only to EGFR^wt (>100-fold) but also to MAO-A/B (>50-fold). Further studies showed that X43 inhibited LSD1 activity and induced the apoptosis of A549 cells in a dose-dependent manner. Meanwhile, compound X43 showed a superior ability to inhibit the proliferation of A549 and THP-1 cells, with IC₅₀ values of 1.62 μM and 1.21 μM, resp. Then, analyses of the stability of human liver microsomes, CYP inhibition and in vivo pharmacokinetics in rats showed that X43 had favorable profiles in vitro and in vivo and the potential for further study. Our findings suggested that a 2-aminopyrimidine-based LSD1 inhibitor deserves further investigation as a treatment for LSD1-overexpressing cancer.

Product Details of C4H5N3, 2-Aminopyrimidine is a useful research compound. Its molecular formula is C4H5N3 and its molecular weight is 95.1 g/mol. The purity is usually 95%.
2-Aminopyrimidine is an organic compound that belongs to the group of pyridines. It has been shown to have antimicrobial, antitumor, and antiviral properties. 2-Aminopyrimidine has been used as a fungicide and herbicide in horticulture and agriculture, respectively. The molecular geometry of this molecule is octahedral with coordination geometry C2v. This chemical binds to the BCR-ABL kinase receptor and inhibits its activity by competitive inhibition of ATP binding. 2-Aminopyrimidine has been shown to have a hematologic response in vivo models and in vitro assays. It also has anti-inflammatory effects when it is taken orally or applied topically., 109-12-6.

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

The nomenclature of pyrimidines is straightforward. However, like other heterocyclics, tautomeric hydroxyl groups yield complications since they exist primarily in the cyclic amide form. 109-12-6, formula is C4H5N3, Name is Pyrimidin-2-amine. For example, 2-hydroxypyrimidine is more properly named 2-pyrimidone. A partial list of trivial names of various pyrimidines exists. Category: pyrimidines.

Wang, Xuefeng;Zhang, Jun;Chen, Qi;Zhou, Wei;Wu, Jie research published 《 Generation of sulfonylureas under photoredox catalysis and their biological evaluations》, the research content is summarized as follows. Traditional synthesis of sulfonylureas largely depends on nucleophilic addition of arylsulfonamides to pre-synthesized isocyanates. Now authors report a new access to alkylsulfonylureas with good yields and broad substrate scope. With the insertion of commercialized chlorosulfonyl isocyanate under photoredox catalysis, alkylsulfonylureas are synthesized in one-pot from the corresponding anilines and silyl enolates. A reaction mechanism is proposed showing the transformation underwent a radical process, and the practicality of this methodol. is proven via application to bioactive mols. Addnl., the anti-cancer and anti-virus screening of these compounds is evaluated.

Category: pyrimidines, 2-Aminopyrimidine is a useful research compound. Its molecular formula is C4H5N3 and its molecular weight is 95.1 g/mol. The purity is usually 95%.
2-Aminopyrimidine is an organic compound that belongs to the group of pyridines. It has been shown to have antimicrobial, antitumor, and antiviral properties. 2-Aminopyrimidine has been used as a fungicide and herbicide in horticulture and agriculture, respectively. The molecular geometry of this molecule is octahedral with coordination geometry C2v. This chemical binds to the BCR-ABL kinase receptor and inhibits its activity by competitive inhibition of ATP binding. 2-Aminopyrimidine has been shown to have a hematologic response in vivo models and in vitro assays. It also has anti-inflammatory effects when it is taken orally or applied topically., 109-12-6.

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia