The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 114040-29-8, name is Ethyl 5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylate. This compound has unique chemical properties. The synthetic route is as follows. Quality Control of Ethyl 5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylate
In 100ml RB flask 2-amino triazole 5-ethyl carboxylate (5gm) was taken. To it 2,4-pentandione (4.1ml) was added followed by addition of piperidine (4ml). This reaction mixture was refluxed for 3 daysunder nitrogen. Reaction mixture was cooled. Solvent from the RM was evaporated. To the residue water was added and neutralized with 6N HCl, solid precipitated. It was filtered and washed with diethyl ether and dried to give pure product as white solid (4 g, 55 %).
With the rapid development of chemical substances, we look forward to future research findings about 114040-29-8.
Reference:
Article; Patil, Vikas; Kale, Manoj; Raichurkar, Anandkumar; Bhaskar, Brahatheeswaran; Prahlad, Dwarakanath; Balganesh, Meenakshi; Nandan, Santosh; Shahul Hameed; Bioorganic and Medicinal Chemistry Letters; vol. 24; 9; (2014); p. 2222 – 2225;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia