Category: 1192711-71-9

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1192711-71-9, name is 2,4-Dichloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine, the common compound, a new synthetic route is introduced below. HPLC of Formula: C7H5Cl2N3

General procedure: A mixture of 2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine 18a (51.3 g) and 1.36 L of 1 N NaOH was stirred at 80 C overnight. The solution was subsequently chilled and adjusted to pH 6 with AcOH. The resulting precipitate was collected, washed with water and dried to afford 19a as solid (37.3 g, yield: 80.7%).

The synthetic route of 1192711-71-9 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Xie, Hui; Zeng, Lili; Zeng, Shaogao; Lu, Xin; Zhang, Guicheng; Zhao, Xin; Cheng, Na; Tu, Zhengchao; Li, Zhiyuan; Xu, Hongjiang; Yang, Ling; Zhang, Xiquan; Huang, Min; Zhao, Junling; Hu, Wenhui; European Journal of Medicinal Chemistry; vol. 52; (2012); p. 205 – 212;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Electric Literature of 1192711-71-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1192711-71-9, name is 2,4-Dichloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine. This compound has unique chemical properties. The synthetic route is as follows.

This compound was prepared following a similar protocol as that presented for Compound 57, except that the starting material used was 2,6-dichloro-8-methyl-7-deazapurine. Briefly, 2,6- dichloro-8-methyl-7-deazapurine (50 mg, 0.25 mmol) was suspended in 1-butanol (3 mL), and DCM (2 mL) was added dropwise until the suspension became a clear solution at room temperature. Pyrrolidine (0.55 mmol) was then added slowly, and the reaction was stirred overnight until TLC analysis (DCM: MeOH 2.5%) indicated it was complete. The mixture was concentrated and the residue dissolved in DCM (20 mL), and the resulting solution was washed with water (2 x 3 mL) to remove the hydrochloride. The solution was then dried over anhydrous Na2S04 and purified by silica gel column chromatography to afford Compound 58 (55 mg, 94% yield); LC-MS m/z = 237.1 [M+l], corresponding CnHi3ClN4.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 1192711-71-9, 2,4-Dichloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine.

Reference:
Patent; SPEROVIE BIOSCIENCES, INC.; IYER, Radhakrishnan, P.; SHERI, Anjaneyulu; PADMANABHAN, Seetharamaiyer; GIMI, Rayormand, H.; CLEARY, Dillon; KHEDKAR, Santosh; CHALLA, Sreerupa; (121 pag.)WO2017/123766; (2017); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia