Category: 14001-60-6

《Reexamination of the application of linear free energy relationships to the azaheterocyclic systems. I. Substituent effects on the basicity of monocyclic azines》 was written by Tomasik, P.; Zalewski, R.. Electric Literature of C6H8N2O And the article was included in Chemicke Zvesti on April 30 ,1977. The article conveys some information:

The basicities of pyridines, pyrimidines, pyridazines, and pyrazines (180 compounds) were correlated with substituent effects by Hammett and Taft equations. Limitations of the LFER are discussed. In addition to this study using 2-Methoxy-4-methylpyrimidine, there are many other studies that have used 2-Methoxy-4-methylpyrimidine(cas: 14001-60-6Electric Literature of C6H8N2O) was used in this study.

2-Methoxy-4-methylpyrimidine(cas: 14001-60-6) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Electric Literature of C6H8N2O

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

《Visible Light-Promoted Aliphatic C-H Arylation Using Selectfluor as a Hydrogen Atom Transfer Reagent》 was written by Zhao, Hong; Jin, Jian. Synthetic Route of C6H8N2O And the article was included in Organic Letters on August 16 ,2019. The article conveys some information:

A mild, practical method for direct arylation of unactivated C(sp3)-H bonds with heteroarenes has been achieved via photochem. Selectfluor is used as a hydrogen atom transfer reagent under visible light irradiation A diverse range of chem. feedstocks, such as alkanes, ketones, esters, and ethers, and complex mols. readily undergo intermol. C(sp3)-C(sp2) bond formation. Moreover, a broad array of heteroarenes, including pharmaceutically useful scaffolds, can be alkylated effectively by the protocol presented here. The experimental process involved the reaction of 2-Methoxy-4-methylpyrimidine(cas: 14001-60-6Synthetic Route of C6H8N2O)

2-Methoxy-4-methylpyrimidine(cas: 14001-60-6) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Synthetic Route of C6H8N2O

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

The author of 《Photochemistry of aromatic compounds. VII. Influence of aliphatic amines on the photochemistry of 5-bromopyrimidines in methanol》 were Nasielski, J.; Kirsch-Demesmaeker, A.; Nasielski-Hinkens, R.. And the article was published in Tetrahedron in 1972. Electric Literature of C6H8N2O The author mentioned the following in the article:

Uv irradiation of 2-methoxy-, 2-phenyl- and 2-dimethylamino-5-bromopyrimidine in MeOH yields the corresponding dehalogenated, methylated and hydroxymethylated compounds Added Et2NH or Et3N strongly increases the rate of dehalogenation. Amines influence the photochemistry of these compounds by transfering an electron to the excited state of the bromopyrimidines. In addition to this study using 2-Methoxy-4-methylpyrimidine, there are many other studies that have used 2-Methoxy-4-methylpyrimidine(cas: 14001-60-6Electric Literature of C6H8N2O) was used in this study.

2-Methoxy-4-methylpyrimidine(cas: 14001-60-6) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Electric Literature of C6H8N2O

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

《Oxidation of 2,4-disubstituted pyrimidines with organic peracids》 was written by Yamanaka, Hiroshi; Ogawa, Shigeru; Sakamoto, Takao. Application of 14001-60-6 And the article was included in Heterocycles on April 1 ,1981. The article conveys some information:

Reaction of 4,6-disubstituted pyrimidines with H2O2 in glacial HOAc gave the corresponding mono N-oxides. However, oxidation of pyrimidine derivatives in which the 6-position is unsubstituted gave both mono N-oxides and ring contracted 2,4-disubstituted imidazoles. In addition to this study using 2-Methoxy-4-methylpyrimidine, there are many other studies that have used 2-Methoxy-4-methylpyrimidine(cas: 14001-60-6Application of 14001-60-6) was used in this study.

2-Methoxy-4-methylpyrimidine(cas: 14001-60-6) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Application of 14001-60-6

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

In 1977,Heterocycles included an article by Sakamoto, Takao; Konno, Shoetsu; Yamanaka, Hiroshi. Computed Properties of C6H8N2O. The article was titled 《Syntheses of pyrimidinyl ketones》. The information in the text is summarized as follows:

Acylpyrimidines were prepared by nitrosation of alkylpyrimidines and hydrolysis of the oximes. Nitrosation of methylpyrimidines and dehydration with POCl3 gave cyanopyrimidines which underwent Grignard reaction with EtMgBr to give ethyldihydropyrimidines. Some acetylpyrimidines were also obtained by homolytic acetylation and underwent Willgerodt-Kindler reaction to give pyrimidinethioacetamides. In the experiment, the researchers used many compounds, for example, 2-Methoxy-4-methylpyrimidine(cas: 14001-60-6Computed Properties of C6H8N2O)

2-Methoxy-4-methylpyrimidine(cas: 14001-60-6) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Computed Properties of C6H8N2O

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

《Studies on pyrimidine derivatives. IV. Synthesis of hydroxymethylpyrimidines by means of homolytic hydroxymethylation》 was published in Heterocycles in 1977. These research results belong to Sakamoto, Takao; Kanno, Kazuko; Ono, Takayasu; Yamanaka, Hiroshi. Reference of 2-Methoxy-4-methylpyrimidine The article mentions the following:

The hydroxymethylpyrimidines I (R = HOCH2, R1 = Me, Ph, MeO, R2 = Me; R = Ph, MeO, R1 = HOCH2, R2 = Me; R = Me, R1 = HOCH2, R2 = Ph, MeO) were prepared by hydroxymethylation of I (R = H or R1 = H) with the hydroxymethyl radical generated from MeOH and (NH4)2S2O8. The experimental process involved the reaction of 2-Methoxy-4-methylpyrimidine(cas: 14001-60-6Reference of 2-Methoxy-4-methylpyrimidine)

2-Methoxy-4-methylpyrimidine(cas: 14001-60-6) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Reference of 2-Methoxy-4-methylpyrimidine

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

《Green oxidant H2O2 as a hydrogen atom transfer reagent for visible light-mediated Minisci reaction》 was published in New Journal of Chemistry in 2019. These research results belong to Zhao, Hong; Li, Zhenlong; Jin, Jian. HPLC of Formula: 14001-60-6 The article mentions the following:

A visible light-mediated “”green”” protocol for metal-free oxidative coupling of heteroarenes and aliphatic C-H components were achieved via a radical pathway. This cross-dehydrogenative coupling method features a broad scope of substrates. The green oxidant H2O2 was used as a hydrogen atom transfer reagent, which was environmentally benign, low cost, and atom economical. In the part of experimental materials, we found many familiar compounds, such as 2-Methoxy-4-methylpyrimidine(cas: 14001-60-6HPLC of Formula: 14001-60-6)

2-Methoxy-4-methylpyrimidine(cas: 14001-60-6) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.HPLC of Formula: 14001-60-6

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Category: pyrimidinesOn October 15, 2010 ,《One-Pot Etherification of Purine Nucleosides and Pyrimidines》 was published in Organic Letters. The article was written by Kokatla, Hari Prasad; Lakshman, Mahesh K.. The article contains the following contents:

A one-pot synthesis of ethers derived from inosine, guanosine, 2′-deoxyguanosine, and pyrimidinones is described. Exposure of the heterocycle to 1H-benzotriazol-1-yl-oxy-tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and Cs2CO3 produces a reactive intermediate, which is converted to the desired ether by subsequent addition of an appropriate alc. or phenol and Cs2CO3. Although rapid formation of HMPA from BOP can occur in the presence of an alc. and base, as demonstrated by the reaction with methanol, under appropriate conditions these heteroaryl ethers can be efficiently synthesized. After reading the article, we found that the author used 2-Methoxy-4-methylpyrimidine(cas: 14001-60-6Category: pyrimidines)

2-Methoxy-4-methylpyrimidine(cas: 14001-60-6) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.Category: pyrimidines

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

《Product class 12: pyrimidines》 was written by von Angerer, S.. Recommanded Product: 2-Methoxy-4-methylpyrimidine And the article was included in Science of Synthesis in 2004. The article conveys some information:

A review. Methods for preparing pyrimidines are reviewed including cyclization, ring transformation, aromatization and substituent modification. After reading the article, we found that the author used 2-Methoxy-4-methylpyrimidine(cas: 14001-60-6Recommanded Product: 2-Methoxy-4-methylpyrimidine)

2-Methoxy-4-methylpyrimidine(cas: 14001-60-6) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Recommanded Product: 2-Methoxy-4-methylpyrimidine

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

《Extrusion of sulfur from [(acylmethyl)thio]pyrimidinones》 was written by Roth, Barbara; Laube, Renee; Tidwell, Mary Y.; Rauckman, Barbara S.. Category: pyrimidines And the article was included in Journal of Organic Chemistry on August 29 ,1980. The article conveys some information:

Thermally mediated S extrusion from the (phenacylthio)pyrimidinones I (R = H, R1 = Br, H, MeO; R = Me, R1 = Br) occurs rapidly in solution at 125° to yield the (benzoylmetheylene)pyrimidinones II. However, III rearranges via an episulfide intermediate to IV. Adjacent 3- or 5-Me substituents in the pyrimidine ring assist S extrusion. No reaction occurs in the absence of a 2-oxo function or on replacement of it by a 2-amino group. On the other hand, 2-amino-4[(1-methylacetonyl)thio]-6(1H)-pyrimidinone cyclizes very readily to give the thieno pyrimidinone V. 2-(Phenacylthio)-4(3H)-pyrimidinones lose S at about one-seventh the rate of the 4-phenacylthio isomers. No thermally mediated reaction occurs with 2-(acetonylthio)-4-pyrimidinones under the conditions described here. In the part of experimental materials, we found many familiar compounds, such as 2-Methoxy-4-methylpyrimidine(cas: 14001-60-6Category: pyrimidines)

2-Methoxy-4-methylpyrimidine(cas: 14001-60-6) is a member of ether. When aromatic ethers are exposed to halogen in the presence or absence of a catalyst, they undergo halogenation, such as bromination.Category: pyrimidines

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia