Application of 142569-70-8, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 142569-70-8, name is (S)-1-(3-(2-(7-Chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propan-1-ol belongs to quinolines-derivatives compound, it is a common compound, a new synthetic route is introduced below.
Stage 2.A 250 mL three-necked flask fitted with a stirrer, thermometer and dropping funnel is flushed with nitrogen. 45 g (0.0983 mol) of 2-(2-(3(S)-(3-(2-(7-chloro-2- quinolinyl)-ethenyl)phenyl)-3-(hydroxypropyl)phenyl)-2-propanol and 120 mL of N,N-dimethylformamide is poured into the flask and stirred until the diol dissolves completely. The content is cooled to between -20 and -15C in the CO2/acetone bath. After cooling 15.7 mL (11.43 g; 0.1130 mol) of triethylamine is added, the temperature is maintained at -20 to -15C and 12.38 g (8.4 mL; 0.1081 mol) of methanesulfonyl chloride is added dropwise over 40 minutes.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, (S)-1-(3-(2-(7-Chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propan-1-ol, other downstream synthetic routes, hurry up and to see.