Category: 160377-42-4

On May 8, 2020, Yan, Tzu-Hsien; Lin, Yi-Hsin; Huang, Chao-Wei published a patent.Related Products of 160377-42-4 The title of the patent was Compound with pyridine ring, synthetic method and application as light-emitting element. And the patent contained the following:

The invention disclosed a kind of pyridine containing compound, its preparation method and application as light-emitting element in OLED. The claimed compound is shown in structure I (ring A and the ring B = (un)substituted pyridine ring; A1,A2 = same or different organic groups; R1,R2 = same or different substituent groups; m,n = 0, 1, 2 or 3). The claimed compound is prepared via coupling etc. multiple steps (procedure given). The prepared compound can be applied as electron transport layer material with good electron mobility. The experimental process involved the reaction of 5-(4-Bromophenyl)pyrimidine(cas: 160377-42-4).Related Products of 160377-42-4

The Article related to pyridine derivative preparation coupling electron transport oled, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.Related Products of 160377-42-4

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On March 1, 1994, Brown, George R.; Mallion, Keith B.; Whittamore, Paul R. O.; Brittain, David R. published a patent.Recommanded Product: 160377-42-4 The title of the patent was Quinuclidine derivatives useful as squalene synthase inhibitors and their preparation. And the patent contained the following:

Compounds of formula I and their pharmaceutically acceptable salts [R1 = H, OH; R2 = H; or R1R2 = bond; X = CH2CH2, CH:CH, CC, CH2O, CH2NH, NHCH2, CH2CO, COCH2, CH2S and SCH2; Ar1 = (un)substituted phenylene; Ar2 = (un)substituted heteroaryl; substituent(s) on Ar1 and Ar2 = halo, OH, (di)(alkyl)amino, NO2, cyano, CO2H, (di)(alkyl)carbamoyl, alkyl, alkenyl, alkynyl, alkoxy, alkoxycarbonyl, alkylthio, alkylsulfinyl, alkylsulfonyl, haloalkyl, carboxyalkyl, alkanoylamino; provided that when R1 = OH, X ≠ NHCH2 or SCH2] are inhibitors of squalene synthase, and hence useful in treating hypercholesterolemia and atherosclerosis. Possible antifungal use is also mentioned (no data). Processes for preparing I and pharmaceutical compositions containing them are also described. For example, coupling of 3-ethynyl-3-hydroxyquinuclidine with 2-(4-bromophenyl)pyridine (preparations given) using Pd(PPh3)2Cl2, CuI, and Et3N in DMF at 90°, gave title compound II. At 2.5 μM, II gave about 98% inhibition of squalene synthase in vitro; it also inhibited cholesterol biosynthesis in rats at an ED50 of 8 mg/kg (route unspecified). The experimental process involved the reaction of 5-(4-Bromophenyl)pyrimidine(cas: 160377-42-4).Recommanded Product: 160377-42-4

The Article related to quinuclidine preparation squalene synthase inhibitor, antihypercholesterolemic quinuclidine preparation, antiatherosclerotic quinuclidine preparation, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.Recommanded Product: 160377-42-4

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On January 12, 2018, Wang, Fang; Li, Chong; Zhang, Zhaochao; Zhang, Xiaoqing published a patent.Computed Properties of 160377-42-4 The title of the patent was Organic compound based on triazine and quinoxaline and its application in organic light-emitting device. And the patent contained the following:

The invention relates to organic compound based on triazine and quinoxaline and its application in organic light-emitting device. The inventive organic compound has high glass transition temperature and mol. thermal stability, has low light absorption and high refractive index in visible light field, and can effectively improve light extraction efficiency of OLED device when applied in CPL layer of OLED device. The inventive compound has deep HOMO level and a high electron mobility, can be applied as hole blocking/electron transporting layer material of OLED device, and can effectively block transportation of hole or energy from light-emitting layer to the side of electron layer, thereby improving recombination efficiency of holes and electrons in light-emitting layer and improving light-emitting efficiency and service life of OLED device. The experimental process involved the reaction of 5-(4-Bromophenyl)pyrimidine(cas: 160377-42-4).Computed Properties of 160377-42-4

The Article related to triazine quinoxaline preparation oled, Heterocyclic Compounds (More Than One Hetero Atom): Triazines and other aspects.Computed Properties of 160377-42-4

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On January 22, 2019, Xing, Qifeng; Li, Zhiyang; Liu, Shuyao; Ren, Xueyan published a patent.HPLC of Formula: 160377-42-4 The title of the patent was Preparation of pyrazoloindazole derivatives and their application in OLED. And the patent contained the following:

The invention relates to pyrazoloindazole derivative of formula I [wherein Ar1 = H, (un)substituted C6-30 aryl or fused aryl, and (un)substituted C3-30 heteroaryl or fused heteroaryl; Ar2 = (un)substituted C6-30 aryl or fused aryl, and (un)substituted C3-30 heteroaryl or fused heteroaryl], method for their preparation and their application in OLED. The inventive compound can be applied in OLED to effectively reduce the work voltage and improve the light-emitting efficiency of the OLED. The experimental process involved the reaction of 5-(4-Bromophenyl)pyrimidine(cas: 160377-42-4).HPLC of Formula: 160377-42-4

The Article related to pyrazoloindazole derivative preparation oled, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazoles and other aspects.HPLC of Formula: 160377-42-4

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On October 30, 2020, Yang, Chuluo; Ni, Fan published a patent.Electric Literature of 160377-42-4 The title of the patent was Chiral organic luminescent material and application thereof in electronic device. And the patent contained the following:

The title chiral organic luminescent material has a structural formula I as shown in claim 1, wherein A1 is alkenyl alkynyl, amino, etc.; A2 is alkenyl alkynyl, amino, etc.; R1-R3 are independently selected from hydrogen, deuterium, etc.; and A1, A2, R1, R2 and R3 are not connected or bonded via covalent bonds. The charge transfer-state chiral organic luminescent material with a D-A structure is formed by introducing a suitable electron acceptor (A) into chiral dihydroindenoacridine as an electron donor (D). The chiral dihydroindenoacridine as the D has large steric hindrance, is favorable for forming large torsion between D and A so as to reduce overlap of frontier mol. orbits, to further reduce the singlet-triplet energy level difference (ΔEST), activate the reverse intersystem crossing process so as to realize delayed fluorescence emission, and improve the exciton utilization rate of the device. The rigid chiral quaternary carbon in the chiral dihydroindenoacridine can enable the chiral organic light-emitting material to have circularly polarized luminescent properties, so that an organic electroluminescent device based on the chiral dihydroindenoacridine has circularly polarized luminescent properties, and effective guarantee is provided for electroluminescence to pass through a quarter-wave plate and a polarizing plate. The chiral organic luminescent material can be applied to electronic devices such as the organic light-emitting device, organic solar cell, organic field effect transistor, organic light emitting field-effect transistor, organic laser, organic sensor or organic spin electronic device. The experimental process involved the reaction of 5-(4-Bromophenyl)pyrimidine(cas: 160377-42-4).Electric Literature of 160377-42-4

The Article related to chiral organic luminescent material preparation oled, Heterocyclic Compounds (More Than One Hetero Atom): Triazines and other aspects.Electric Literature of 160377-42-4

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On July 14, 2017, Zhang, Zhaochao; Tang, Dandan; Li, Chong published a patent.Reference of 5-(4-Bromophenyl)pyrimidine The title of the patent was Organic compound based on triazine and benzimidazole as core and application in organic electroluminescence device. And the patent contained the following:

The invention disclosed a kind of organic compound based on triazine and benzimidazole as core, its preparation method and application in organic electroluminescence device. The claimed compound is shown in structure I (x = 1 or 2; z = 1 or 2; m,n = 0, 1, or 2, and m+n+z = 3; Ar1,Ar2,Ar3 = C1-10 alkyl, or halogen atom, protium, deuterium, tritium substituted or unsubstituted Ph, naphthyl, di-Ph or pyridyl, pyrimidyl, pyrazinyl, pyridazinyl, dibenzofuran, etc.; R1 = C1-10 alkyl, or halogen atom, protium, deuterium, tritium substituted or unsubstituted Ph, naphthyl, etc.; R2,R3 = (un)substituted benzoimidazoyl). The claimed compound is prepared via coupling etc. multiple steps (procedure given). The prepared compound has higher glass transition temperature and mol. thermal stability, low absorption and high refractive index in visible light field, and light extraction efficiency of OLED device can be effectively improved after the compound is applied to the CPL layer of OLED device. The prepared compound also has deep HOMO energy level and high electron mobility, and can be used as hole blocking / electron transport layer material for OLED device to effectively block hole or energy from being transmitted to the electron layer side from the luminescent layer, thus improving recombination efficiency of hole and electron in the luminescent layer so as to improve luminous efficiency and service life of OLED device. The experimental process involved the reaction of 5-(4-Bromophenyl)pyrimidine(cas: 160377-42-4).Reference of 5-(4-Bromophenyl)pyrimidine

The Article related to triazine benzimidazole based core derivative preparation coupling green oled, Heterocyclic Compounds (More Than One Hetero Atom): Triazines and other aspects.Reference of 5-(4-Bromophenyl)pyrimidine

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On May 8, 2020, Yan, Tzu-Hsien; Lin, Yi-Hsin; Huang, Chao-Wei published a patent.Related Products of 160377-42-4 The title of the patent was Compound with pyridine ring, synthetic method and application as light-emitting element. And the patent contained the following:

The invention disclosed a kind of pyridine containing compound, its preparation method and application as light-emitting element in OLED. The claimed compound is shown in structure I (ring A and the ring B = (un)substituted pyridine ring; A1,A2 = same or different organic groups; R1,R2 = same or different substituent groups; m,n = 0, 1, 2 or 3). The claimed compound is prepared via coupling etc. multiple steps (procedure given). The prepared compound can be applied as electron transport layer material with good electron mobility. The experimental process involved the reaction of 5-(4-Bromophenyl)pyrimidine(cas: 160377-42-4).Related Products of 160377-42-4

The Article related to pyridine derivative preparation coupling electron transport oled, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.Related Products of 160377-42-4

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On March 1, 1994, Brown, George R.; Mallion, Keith B.; Whittamore, Paul R. O.; Brittain, David R. published a patent.Recommanded Product: 160377-42-4 The title of the patent was Quinuclidine derivatives useful as squalene synthase inhibitors and their preparation. And the patent contained the following:

Compounds of formula I and their pharmaceutically acceptable salts [R1 = H, OH; R2 = H; or R1R2 = bond; X = CH2CH2, CH:CH, CC, CH2O, CH2NH, NHCH2, CH2CO, COCH2, CH2S and SCH2; Ar1 = (un)substituted phenylene; Ar2 = (un)substituted heteroaryl; substituent(s) on Ar1 and Ar2 = halo, OH, (di)(alkyl)amino, NO2, cyano, CO2H, (di)(alkyl)carbamoyl, alkyl, alkenyl, alkynyl, alkoxy, alkoxycarbonyl, alkylthio, alkylsulfinyl, alkylsulfonyl, haloalkyl, carboxyalkyl, alkanoylamino; provided that when R1 = OH, X ≠ NHCH2 or SCH2] are inhibitors of squalene synthase, and hence useful in treating hypercholesterolemia and atherosclerosis. Possible antifungal use is also mentioned (no data). Processes for preparing I and pharmaceutical compositions containing them are also described. For example, coupling of 3-ethynyl-3-hydroxyquinuclidine with 2-(4-bromophenyl)pyridine (preparations given) using Pd(PPh3)2Cl2, CuI, and Et3N in DMF at 90°, gave title compound II. At 2.5 μM, II gave about 98% inhibition of squalene synthase in vitro; it also inhibited cholesterol biosynthesis in rats at an ED50 of 8 mg/kg (route unspecified). The experimental process involved the reaction of 5-(4-Bromophenyl)pyrimidine(cas: 160377-42-4).Recommanded Product: 160377-42-4

The Article related to quinuclidine preparation squalene synthase inhibitor, antihypercholesterolemic quinuclidine preparation, antiatherosclerotic quinuclidine preparation, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.Recommanded Product: 160377-42-4

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On January 12, 2018, Wang, Fang; Li, Chong; Zhang, Zhaochao; Zhang, Xiaoqing published a patent.Computed Properties of 160377-42-4 The title of the patent was Organic compound based on triazine and quinoxaline and its application in organic light-emitting device. And the patent contained the following:

The invention relates to organic compound based on triazine and quinoxaline and its application in organic light-emitting device. The inventive organic compound has high glass transition temperature and mol. thermal stability, has low light absorption and high refractive index in visible light field, and can effectively improve light extraction efficiency of OLED device when applied in CPL layer of OLED device. The inventive compound has deep HOMO level and a high electron mobility, can be applied as hole blocking/electron transporting layer material of OLED device, and can effectively block transportation of hole or energy from light-emitting layer to the side of electron layer, thereby improving recombination efficiency of holes and electrons in light-emitting layer and improving light-emitting efficiency and service life of OLED device. The experimental process involved the reaction of 5-(4-Bromophenyl)pyrimidine(cas: 160377-42-4).Computed Properties of 160377-42-4

The Article related to triazine quinoxaline preparation oled, Heterocyclic Compounds (More Than One Hetero Atom): Triazines and other aspects.Computed Properties of 160377-42-4

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On January 22, 2019, Xing, Qifeng; Li, Zhiyang; Liu, Shuyao; Ren, Xueyan published a patent.HPLC of Formula: 160377-42-4 The title of the patent was Preparation of pyrazoloindazole derivatives and their application in OLED. And the patent contained the following:

The invention relates to pyrazoloindazole derivative of formula I [wherein Ar1 = H, (un)substituted C6-30 aryl or fused aryl, and (un)substituted C3-30 heteroaryl or fused heteroaryl; Ar2 = (un)substituted C6-30 aryl or fused aryl, and (un)substituted C3-30 heteroaryl or fused heteroaryl], method for their preparation and their application in OLED. The inventive compound can be applied in OLED to effectively reduce the work voltage and improve the light-emitting efficiency of the OLED. The experimental process involved the reaction of 5-(4-Bromophenyl)pyrimidine(cas: 160377-42-4).HPLC of Formula: 160377-42-4

The Article related to pyrazoloindazole derivative preparation oled, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazoles and other aspects.HPLC of Formula: 160377-42-4

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia