Synthetic Route of 18593-44-7, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 18593-44-7, name is 5,6-Dimethylthieno[2,3-d]pyrimidin-4(3H)-one. This compound has unique chemical properties. The synthetic route is as follows.
General procedure: A solution of 4-hydroxy-5,6,7,8-tetrahydrobenzothieno[2,3-d] pyrimidine (1.0 g, 4.85 mmol) in phosphorous oxychloride (10 mL) was heated to 90 oC for 3 h. Excess phosphorus oxychloride was removed in vacuo and then ice-water (40 mL) was added. The solution was then basified by addition of solid sodium hydrogen carbonate in small portions. The precipitate that resulted was filtered off, washing with water to obtain an off-white solid (1.0 g, 92%)
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 18593-44-7, 5,6-Dimethylthieno[2,3-d]pyrimidin-4(3H)-one.
Reference:
Article; Sleebs, Brad E.; Nikolakopoulos, George; Street, Ian P.; Falk, Hendrik; Baell, Jonathan B.; Bioorganic and Medicinal Chemistry Letters; vol. 21; 19; (2011); p. 5992 – 5994;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia