Category: 23256-42-0

On November 11, 1987, Jooji, Eru Euansu; Debora, Eru Deuookusu published a patent.Application In Synthesis of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate The title of the patent was Pathogenic Neisseria-specific growth medium and its use in clinical diagnosis. And the patent contained the following:

A medium containing vancomycin (I) and lincomycin (II) for selectively growing Neisseria is prepared Its use in clin. diagnosis of pathogenic Neisseria such as N. gonorrhoeae or N. meningitidis is also disclosed. An agar medium containing GC agar base 36.0, Hb 10.0 g/L, Isovitalex enrichment 10.0 mL/L, I 2.0 mg/L, II 1.0, colistin sulfate 7.5, trimethoprim 5.0, amphotericin B 5.0 μg/L, and nystatin 1250 units/L was prepared and tested for its selectivity. The growth of N. gonorrhoeae and N. meningitidis was excellent while growth of other microorganisms such as yeast was inhibited. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Application In Synthesis of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

The Article related to neiserria pathogen selection culture medium, vancomycin lincomycin neiserria pathogen selection, Fermentation and Bioindustrial Chemistry: Methods (Including Analysis) and other aspects.Application In Synthesis of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On December 24, 2014, Wang, Heshan published a patent.Application of 23256-42-0 The title of the patent was Coating material containing white ointment and manufacture method. And the patent contained the following:

Title coating material is manufactured from white ointment 1-2, trimethoprim lactate 0.5-1, tetrabutylammonium bromide 1-2, sodium carbonate 2-3, allyl poly(ethylene glycol) 1-2, celestite powder 6-10, precipitated silica 5-8, dibutyltin dilaurate 0.8-1, polyacrylamide 0.8-1, styrene 120-160, Me acrylate 80-100, Bu methacrylate 40-60, ammonium peroxydisulfate 3-4, OP-10 6-8, bonding additive 5-7, and deionized water 500-600 weight parts. The bonding additive is manufactured from isobornyl acrylate 6-8, acrylic-silicone emulsion 25-30, microcapsule rose essential oil 2-3, dimethylaminoethyl methacrylate 4-6, potassium persulfate 1-2, redwood powder 2-3, poly(N-vinylpyrrolidone) 0.6-1, and deionized water 10-16 weight parts. The invention also provides methods for manufacturing the title coating material and the bonding additive. The white ointment in the title coating material effectively improves compatibility among the materials, promotes uniform and leveling of coating film, and improves film-forming effect and adhesion. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Application of 23256-42-0

The Article related to coating white ointment manufacture, Coatings, Inks, and Related Products: Acrylic and Water-Sol (Electrophoretic) Resin Coatings and other aspects.Application of 23256-42-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On March 6, 2018, Yu, Haobo; He, Yang; Chen, Changfeng; Yu, Yanzhao; Jiang, Ruijing published a patent.HPLC of Formula: 23256-42-0 The title of the patent was Preparation method of antibacterial corrosion inhibitor for oil field water treatment system. And the patent contained the following:

The title antibacterial corrosion inhibitor is prepared from (by weight) dodecyldimethylbenzylammonium halide (dodecyldimethylbenzylammonium chloride and/or dodecyldimethylbenzylammonium bromide) 5-60%, antibacterial synergistic agent (trimethoprim and/or trimethoprim lactate) 0.5-5%, surfactant (nonyl phenol polyoxyethylene ether and/or octyl phenol polyoxyethylene ether) 10-30%, buffer (sodium hydrogen phosphate and/or sodium dihydrogen phosphate) 3-10% and water in balance by mixing. The antibacterial corrosion inhibitor has high sterilization efficiency to sulfate reducing bacteria (SRB) and saprophytic bacteria (TGB), and has the advantages of long-acting drug effect, no drug resistance, simple production process and low cost as well as good corrosion inhibition effect on CO2 corrosion. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).HPLC of Formula: 23256-42-0

The Article related to oil field water treatment system antibacterial corrosion inhibitor, Fossil Fuels, Derivatives, and Related Products: Lubricants and Functional Fluids and other aspects.HPLC of Formula: 23256-42-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On July 8, 2015, Wang, Guidong; Song, Rui published a patent.SDS of cas: 23256-42-0 The title of the patent was A kind of composite saponification cutting fluid. And the patent contained the following:

The invention discloses a kind of composite saponification cutting fluid, which is made up of the following raw materials by weight parts: oleic acid 2-3, trimethoprim lactate 0.1-0.2, Na myristate 3-5, p-nitrophenol 0.2-0.4, castor oil polyoxyethylene ether 0.1-0.2, KOH 0.3-0.5, glyceryl carboxylate 0.2-0.3, polyethylene glycol diglycidyl ether 5-7, raw silk 10-13, polymaleic anhydride 10-16, Span 80 0.8-2, and deionized H2O 170-200. The preparation method includes the following steps: (1) adding raw silk to 0.4-0.6% Na carbonate solution, soaking at 98-100° for 60-80 min, filtrating, drying, mixing with trimethoprim lactate, grinding, adding Span-80, deionized H2O, stirring, adding polyethylene glycol diglycidyl ether, mixing and ultrasonic treating for 30-35 min, obtaining fibroin emulsion; (2) taking KOH, adding deionized H2O, stirring, adding oleic acid, heating to 70-80°C, adding Na myristate and p-nitrophenol, insulating and reacting for 30-40 min, obtaining composite saponification liquid; (3) mixing the fibroin emulsion with polymaleic anhydride, standing at 65-70°C for 30-40 min, adding composite saponification liquid, stirring for 10-16 min, obtaining antirust blended emulsion; (4) mixing the antirust blended emulsion with the residual raw materials, stirring for 20-30 min, obtaining cutting fluid. The composite saponification liquor added in cutting fluid of the present invention has excellent extreme pressure and antiwear behavior, can provide long lasting abrasion and corrosion protection. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).SDS of cas: 23256-42-0

The Article related to composite saponification cutting fluid lubricating oil additive, Fossil Fuels, Derivatives, and Related Products: Lubricants and Functional Fluids and other aspects.SDS of cas: 23256-42-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On January 7, 2015, Sun, Jufu; Dai, Yujun; Zhu, Penxin published a patent.Computed Properties of 23256-42-0 The title of the patent was Antibacterial anticorrosive coatings. And the patent contained the following:

The coatings contain trimethoprim lactate 0.7-1, polyoxymethylene 2-3, ammonium polyphosphate 2-3, turpentine 0.6-1, illite powders 6-8, β-hydroxyalkyl amides 1-2, 2-bromo-4-methylphenol 1-2, precipitated silica 6-10, crosslinking agent TAC 0.5-1, diisocyanates 0.4-1, styrene 140-200, epoxidized soybean oil 2-3, deionized water 500-600, isooctyl acrylate 140-200, sodium persulfate 3-6, OP-10 5-7, and bonding aids 4-5 parts. The bonding aids are prepared from alumina sol, ammonium aluminum sulfate, lanolin, polyethylene glycol dimethacrylate, anhydrous ethanol, isooctyl acrylate, potassium sulfate, OP-10, rosewood micropowders, and deionized water. The coatings have good adhesion and weather resistance. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Computed Properties of 23256-42-0

The Article related to antibacterial anticorrosive acrylate coating weather resistance, Coatings, Inks, and Related Products: Acrylic and Water-Sol (Electrophoretic) Resin Coatings and other aspects.Computed Properties of 23256-42-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On December 16, 2015, Liang, Ruiyong; Gao, Hai published a patent.SDS of cas: 23256-42-0 The title of the patent was Environmentally friendly waterborne coating compositions. And the patent contained the following:

The compositions, having low VOC content, contain waterborne acrylic emulsions 91-100, polydicyclopentadiene 1-2, ammonium molybdate 0.5-1, iron trifluoroacetylacetonate 0.1-0.2, polypropylene glycol 1-2, potassium silicate 1-2, octyl epoxystearate 2-4, 2-mercaptobenzimidazole 0.5-1, ultrafine barium sulfate 10-12, polymethyl acrylate 2-3, dodecyl di-Me amine oxide 0.3-1, flame retardant aids 2-4, ethylene glycol Bu ether 2-3, and deionized water 20-30 parts. The flame retardant aids contain microcapsulated red phosphorus, polycarbonates, aluminum magnesium silicate, lithium-based bentonite, trimethoprim lactate, trimethylolpropane, and isooctyl acrylate. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).SDS of cas: 23256-42-0

The Article related to flame retardant acrylic emulsion waterborne coating composition, Coatings, Inks, and Related Products: Acrylic and Water-Sol (Electrophoretic) Resin Coatings and other aspects.SDS of cas: 23256-42-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On January 27, 2011, Yoshida, Masaru; Azuma, Takeshi; Yamamoto, Koji; Nishitani, Yosuke published a patent.Quality Control of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate The title of the patent was Method and nutritive media for in vitro culture of Helicobacter heilmannii, culture products, and method for separation and detection of the Helicobacter. And the patent contained the following:

The nutritive media contain base media and catalase. The culture products contain Helicobacter heilmannii and no other microorganisms. Thus, oral administration of homogenized pig gastric mucosa to mouses, homogenization of the mouse gastric mucosa, culture of the homogenized products in a sheep blood-added trypticase soy agar culture medium containing catalase, and culture of the resulting colony two times gave a culture product, which was subjected to urease gene anal. to show high base sequence homol. with urease base sequence from in vivo-cultured Helicobacter heilmannii. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Quality Control of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

The Article related to nutritive media culture helicobacter separation detection catalase, helicobacter culture sheep blood trypticase soy agar, pig gastric mucosa helicobacter urease sequence detection and other aspects.Quality Control of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Brumfitt, W.; Hamilton-Miller, J. M. T.; Grey, Daphne published an article in 1977, the title of the article was Antibacterial activity of combinations of clindamycin and antifolate agents.Quality Control of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate And the article contains the following content:

The antibacterial activities of clindamycin-HCl (I-HCl) [21462-39-5] in combination with the folate antagonists trimethoprim lactate [23256-42-0] or sulfamethoxazole [723-46-6] were only additive, suggesting that I is not an antifolate agent. Thus, some other mechanism of action must be responsible for the therapeutic effects of I against malaria and toxoplasmosis, conditions known to be susceptible to treatment with antifolate compounds Inhibition of protein synthesis is the most likely explanation for the action of I, but other antibiotics which inhibit bacterial protein synthesis have generally shown little activity against malaria. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Quality Control of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

The Article related to clindamycin bactericidal action, trimethoprim clindamycin bactericidal activity, sulfamethoxazole clindamycin bactericidal activity, folate antagonist clindamycin bacteria and other aspects.Quality Control of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On January 27, 2011, Yoshida, Masaru; Azuma, Takeshi; Yamamoto, Koji; Nishitani, Yosuke published a patent.Quality Control of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate The title of the patent was Method and nutritive media for in vitro culture of Helicobacter heilmannii, culture products, and method for separation and detection of the Helicobacter. And the patent contained the following:

The nutritive media contain base media and catalase. The culture products contain Helicobacter heilmannii and no other microorganisms. Thus, oral administration of homogenized pig gastric mucosa to mouses, homogenization of the mouse gastric mucosa, culture of the homogenized products in a sheep blood-added trypticase soy agar culture medium containing catalase, and culture of the resulting colony two times gave a culture product, which was subjected to urease gene anal. to show high base sequence homol. with urease base sequence from in vivo-cultured Helicobacter heilmannii. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Quality Control of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

The Article related to nutritive media culture helicobacter separation detection catalase, helicobacter culture sheep blood trypticase soy agar, pig gastric mucosa helicobacter urease sequence detection and other aspects.Quality Control of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Brumfitt, W.; Hamilton-Miller, J. M. T.; Grey, Daphne published an article in 1977, the title of the article was Antibacterial activity of combinations of clindamycin and antifolate agents.Quality Control of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate And the article contains the following content:

The antibacterial activities of clindamycin-HCl (I-HCl) [21462-39-5] in combination with the folate antagonists trimethoprim lactate [23256-42-0] or sulfamethoxazole [723-46-6] were only additive, suggesting that I is not an antifolate agent. Thus, some other mechanism of action must be responsible for the therapeutic effects of I against malaria and toxoplasmosis, conditions known to be susceptible to treatment with antifolate compounds Inhibition of protein synthesis is the most likely explanation for the action of I, but other antibiotics which inhibit bacterial protein synthesis have generally shown little activity against malaria. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Quality Control of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

The Article related to clindamycin bactericidal action, trimethoprim clindamycin bactericidal activity, sulfamethoxazole clindamycin bactericidal activity, folate antagonist clindamycin bacteria and other aspects.Quality Control of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia