Category: 23256-42-0

On March 22, 2019, Shen, Lianbing; Chen, Yongqiang; Zhou, Yiping; Zhang, Anlian published a patent.Product Details of 23256-42-0 The title of the patent was Easily soluble compound sulfachloropyridazine sodium powder. And the patent contained the following:

The invention discloses a soluble compound sulfachloropyridazine sodium powder with high water solubility and good quality. The compound sulfachloropyridazine sodium powder comprises the following raw materials: sulfachloropyridazine sodium, trimethoprim and D-sucrose. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Product Details of 23256-42-0

The Article related to solubility sulfachloropyridazine sodium, Pharmaceuticals: Formulation and Compounding and other aspects.Product Details of 23256-42-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On October 26, 2016, Zhang, Ronghao; Shao, Zhigang; Hou, Qiang published a patent.Reference of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate The title of the patent was Medicine for treating salpingitis of laying poultry. And the patent contained the following:

The present invention discloses a medicine for treating salpingitis of laying poultry, which comprises raw materials by weight part: Scutellaria baicalensis 6-8, Paeonia suffruticosa 5-10, Panax japonicus 3-5, Agrimonia pilosa 5-7, Corydalis yanhusuo 7-8, Radix Paeoniae Rubra 4-6, Herba Epimedii 6-8, Cnidium monnieri 2-4, Hordeum vulgare 6-10, medicated leaven 8-10, Melia toosendan 2-4, Euryale ferox 5-8, Luffa cylindrica 12-16, Cuscuta chinensis 6-10, Manis pentadactyla 2-4, Clausena excavata 4-6, Solidago decurens 6-8, Trollius macropetalus 1-3, amoxicillin 80-100, ciprofloxacin 80-100, lactic acid TMP 20-25, anhydrous sodium sulfate 650-700, and glucose powder 120-150. The invention has scientific medicines compatibility, simple administration in combination with feed, lower cost, no drug residue and toxic side effect. Combination of all medicines has effects such as effectively clearing heat and detoxicating, replenishing qi to invigorate the spleen, promoting blood circulation and hemostasis, and significant therapeutic effect to salpingitis of oviparous poultries, which effectively improves egg laying rate of laying birds, greatly increases the economic benefit of farmer. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Reference of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

The Article related to medicine salpingitis laying poultry, Pharmaceuticals: Formulation and Compounding and other aspects.Reference of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On September 21, 2016, Yang, Caiyun published a patent.Related Products of 23256-42-0 The title of the patent was Compound care agent for treating chronic pyelonephritis and preparation method thereof. And the patent contained the following:

The present invention discloses a compound care agent for treating chronic pyelonephritis and preparation method thereof. The compound care agent for treating chronic pyelonephritis comprises sulfamethazine, trovafloxacin mesylate, clavulanate potassium, coated aldehyde starch oxide, imipenem, finasteride, tocopheryl acetate, coptisine, proglumetacin dipeptide, colloidal bismuth subcitrate, demetionine 1,4-butanedisulfonate, trimethoprim lactate, and vitamin C. The compound care agent of the present invention has antibacterial anti-inflammatory, nourishing liver and kidney, Qi and blood, and detoxification effects, and can effectively eliminate inflammation, repair renal function, promote kidney metabolism, and improve the immunity of the patients. Proved by clin., the compound agent of the invention for the treatment of chronic pyelonephritis, has obvious curative effect, high safety, low side effects, and good long term application prospect. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Related Products of 23256-42-0

The Article related to care agent chronic pyelonephritis, Pharmaceuticals: Formulation and Compounding and other aspects.Related Products of 23256-42-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On August 28, 2020, Tang, Fayin published a patent.Application of 23256-42-0 The title of the patent was The preparation method of a Florfenicol powder for improving water solubility. And the patent contained the following:

The invention relates to the preparation method of a florfenicol powder for improving water solubility as well as aand an applications. The powder is composed of the following components in parts by weight: 10 parts of florfenicol powder, 3-5 parts of citric acid, 2-3 parts of polyvinylpyrrolidone PVPK30, 50-60 parts of lactose, 2-4 parts of sodium lauryl sulfate, 5-7 parts of polyethylene glycol 6000, 2-3 parts of trimethoprim lactate and 2-4 parts of palm oil. Polyethylene glycol 6000, citric acid, polyvinylpyrrolidone PVPK30, lactose, sodium dodecyl sulfate and the palm oilare adopted and various components are synergetic to improve water solubility of florfenicol and trimethoprim lactate, so that the curative effect of the florfenicol powder is optimal. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Application of 23256-42-0

The Article related to florfenicol water solubility, Pharmaceuticals: Formulation and Compounding and other aspects.Application of 23256-42-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On June 16, 1980, Quintanilla Almacro, Eliseo published a patent.Safety of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate The title of the patent was Trimethoprim lactate. And the patent contained the following:

The title compound (I lactate) [23256-42-0] was prepared by addition of lactic acid in CHCl3 to the free base to increase the bioavailability of I, for example, from suppositories. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Safety of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

The Article related to trimethoprim lactate, Pharmaceuticals: Formulation and Compounding and other aspects.Safety of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On July 22, 2015, Wang, Bin; Li, Xuting; Li, Jinliang published a patent.Reference of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate The title of the patent was Composition for treating diarrhea in livestock and poultry and preparation method thereof. And the patent contained the following:

The title composition for treating diarrhea in livestock and poultry comprises norfloxacin lactate, mequindox, trimethoprim lactate, atropine and adjuvant (DMSO, etc.), and can be formulated into granules, tablets, powders, unguents or injections. The invention also provides a preparation method of the composition The inventive composition has quick action, good antimicrobial effect, reduced probability of drug resistance of bacteria, increased antimicrobial sensitivity, simple preparation process, and no drug residue, can prevent infection and secondary infection, and is suitable for treating diarrhea in livestock and poultry. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Reference of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

The Article related to veterinary medicine norfloxacin lactate mequindox trimethoprim atropine, Pharmaceuticals: Formulation and Compounding and other aspects.Reference of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On April 2, 2014, Liu, Changdou published a patent.Electric Literature of 23256-42-0 The title of the patent was Compound dimetridazole premix for controlling avian enterovirus syndrome. And the patent contained the following:

The invention discloses compound dimetridazole premix for controlling avian enterovirus syndrome, comprising by weight%: dimetridazole 10-30, neomycin sulfate 4-10, decoquinate 2-8, lysozyme 10-30, etamsylate 0.5-5, lactic acid TMP 3-10, and pharmaceutically suitable excipients as balance. The invention adopts new and efficient decoquinate as the anticoccidial drugs, has special effect on intestinal infection dimetridazole and neomycin sulfate, has antibacterial, antiviral, anti-inflammatory pain, intestinal mucosa repair effect of lysozyme, efficient hemostatic drug etamsylate and drug synergistic agent in the compound preparation, and has treatment efficiency on avian enterovirus syndrome. The formula is reasonable, scientific, has simple preparation, wide application, can be used as the preferred drug for prevention and treatment of poultry intestinal toxin syndrome. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Electric Literature of 23256-42-0

The Article related to dimetridazole neomycin sulfate decoquinate avian enterovirus syndrome, Pharmaceuticals: Formulation and Compounding and other aspects.Electric Literature of 23256-42-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On August 1, 2007, Wei, Zongsheng; Geng, Qiangbin; Guo, Jianhua published a patent.Recommanded Product: 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate The title of the patent was Compounded berberine sulfate injection and its preparation method. And the patent contained the following:

The title injection is composed of berberine sulfate 5-30, mequindox 5-35, trimethoprim lactate 1-25 and atropine 0.5-2 weight parts. The method for preparing the injection comprises dissolving berberine sulfate in hot injection water, stirring to obtain solution A, adding mequindox and niacinamide, stirring to obtain solution B, adding trimethoprim lactate and atropine, stirring, adjusting pH to 4-6 with 10% sulfuric acid, adsorbing with 0.1% activated C for 15-20 min and adding injection water to 1000 weight parts. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Recommanded Product: 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

The Article related to antibacterial agent berberine sulfate injection preparation dysentery, Pharmaceuticals: Formulation and Compounding and other aspects.Recommanded Product: 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On February 5, 2014, there was a patent about bacterial infection.Recommanded Product: 23256-42-0 The title of the patent was Compound veterinary drug preparation for treating enteritis type colibacillosis of poultry. And the patent contained the following:

The invention belongs to compound veterinary drug preparation for treating enteritis type colibacillosis of poultry. The preparation comprises the following components: neomycin sulfate, TMP lactate, and glutamine as main components, and adjuvants, wherein neomycin sulfate 3.25 weight%, TMP lactate 0.81 weight%, glutamine 10 weight%, the adjuvant is glucose, the ratio of adjuvant is 85.94 weight%. The veterinary composition is used for treating enteritis type colibacillosis of poultry. The processing technol. of the composition includes grinding and sieving each component, weighing accurately according to the required proportion, mixing for 25 min, inspecting the semi-finished product quality, packaging, and inspecting the finished product quality to obtain the final product. The invention has obvious curative effect on enteritis type colibacillosis, has low drug resistance, safety, and low toxicity, and has very good popularization and application value. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Recommanded Product: 23256-42-0

The Article related to neomycin sulfate trimethoprim lactate glutamine powder colibacillosis, Pharmaceuticals: Formulation and Compounding and other aspects.Recommanded Product: 23256-42-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

On December 12, 2012, Zhou, Qingfu; Liu, Wenli published a patent.HPLC of Formula: 23256-42-0 The title of the patent was Doxycycline hydrochloride-containing composition for preventing and treating colibacillosis and chronic respiratory disease of poultry and preparation method thereof. And the patent contained the following:

Title composition is composed of doxycycline hydrochloride 10-15, colistin sulfate 10-20, tylosin tartrate 5-15, trimethoprim lactate 5-10, and anhydrous glucose 40-70 weight parts, and is prepared by mixing doxycycline hydrochloride, colistin sulfate and anhydrous glucose 20-30 weight parts for 5-10min, mixing tylosin tartrate, trimethoprim lactate and anhydrous glucose 10-25 weight parts for 5-10min, merging the two mixture, adding residual anhydrous glucose, mixing for 10-15min, and mixing uniformly. The doxycycline hydrochloride-containing composition can be used for preventing and treating colibacillosis and chronic respiratory disease of poultry and has advantages of simple preparation process and good therapeutic effect. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).HPLC of Formula: 23256-42-0

The Article related to doxycycline hydrochloride colibacillosis respiratory disease poultry, Pharmaceuticals: Formulation and Compounding and other aspects.HPLC of Formula: 23256-42-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia