Category: 23906-13-0

Synthetic Route of 23906-13-0, Adding some certain compound to certain chemical reactions, such as: 23906-13-0, name is 2-Hydrazinyl-4,6-dimethylpyrimidine,molecular formula is C6H10N4, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 23906-13-0.

General procedure: An ethanolic solution (25 mL) of 2-hydrazino-4,6-dimethylpyrimidine 1 (0.27 g, 2 mmol) and trifluoromethyl-bdiketones 2a-c (2 mmol) was refluxed for 7 h. The reaction was monitored by tlc. On completion of reaction, solvent was evaporated in vacuo and the solid obtained was recrystallized from ethanol. The tlc and 1H NMR of the reaction mixture showed the formation of a single product 3a-c.

According to the analysis of related databases, 23906-13-0, the application of this compound in the production field has become more and more popular.

Reference:
Article; Aggarwal, Ranjana; Bansal, Anshul; Rozas, Isabel; Kelly, Brendan; Kaushik, Pawan; Kaushik, Dhirender; European Journal of Medicinal Chemistry; vol. 70; (2013); p. 350 – 357;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Synthetic Route of 23906-13-0, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 23906-13-0, name is 2-Hydrazinyl-4,6-dimethylpyrimidine. This compound has unique chemical properties. The synthetic route is as follows.

1.0 mM of 4-diethylamino salicylaldehyde was dissolved inmethanol (5 mL) and a hot solution of 1.0 mM 3, 5-dimethyl2-hydrazino pyrimidine in 2 mL methanol was added drop wise toit. After stirring overnight and then reducing the volume to3 mL,deep yellow crystals were obtained. It was washed with coldmethanol and dried in vacuum overnight. Yield: 68%.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 23906-13-0, 2-Hydrazinyl-4,6-dimethylpyrimidine.

Reference:
Article; Makhal, Subhash Chandra; Bhattacharyya, Arghyadeep; Ghosh, Soumen; Guchhait, Nikhil; Journal of Photochemistry and Photobiology A: Chemistry; vol. 358; (2018); p. 138 – 146;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Synthetic Route of 23906-13-0, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 23906-13-0, name is 2-Hydrazinyl-4,6-dimethylpyrimidine. This compound has unique chemical properties. The synthetic route is as follows.

1.0 mM of 4-diethylamino salicylaldehyde was dissolved inmethanol (5 mL) and a hot solution of 1.0 mM 3, 5-dimethyl2-hydrazino pyrimidine in 2 mL methanol was added drop wise toit. After stirring overnight and then reducing the volume to3 mL,deep yellow crystals were obtained. It was washed with coldmethanol and dried in vacuum overnight. Yield: 68%.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 23906-13-0, 2-Hydrazinyl-4,6-dimethylpyrimidine.

Reference:
Article; Makhal, Subhash Chandra; Bhattacharyya, Arghyadeep; Ghosh, Soumen; Guchhait, Nikhil; Journal of Photochemistry and Photobiology A: Chemistry; vol. 358; (2018); p. 138 – 146;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 23906-13-0, name is 2-Hydrazinyl-4,6-dimethylpyrimidine. This compound has unique chemical properties. The synthetic route is as follows. Product Details of 23906-13-0

EXAMPLE 6 Synthesis of 3-(3,4-dimethylphenyl)-1-(4,6-dimethyl-2-pyrimidinyl)-1,4,5,6-tetrahydropyridazine To a stirred solution of 4,6-dimethyl-2-hydrazinopyrimidine (500 mg, 3.62 mmol) in 7.2 mL of acetic acid under nitrogen is added 4-chloro-1-(3,4-dimethyl-phenyl)-1-butanone (763 mg, 3.62 mmol). The solution is stirred at 25C overnight. Acetic acid is removed. The residue is taken up in dilute sodium bicarbonate solution, extracted with dichloromethane twice, dried (MgSO4) and concentrated to give the intermediate hydrazone as a brown oily solid (1.21 g). A portion of this solid (200 mg, 0.60 mmol) is dissolved in 3 mL of anhydrous THF and stirred under nitrogen.

With the rapid development of chemical substances, we look forward to future research findings about 23906-13-0.

Reference:
Patent; E.I. DU PONT DE NEMOURS AND COMPANY; EP515041; (1992); A2;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 23906-13-0, name is 2-Hydrazinyl-4,6-dimethylpyrimidine. A new synthetic method of this compound is introduced below., Computed Properties of C6H10N4

II) The control compound DYMDAB was obtained by refluxing an equimolar mixture of 4-dimethylaminobenzaldehyde with 3, 5-dimethyl 2-hydrazino pyrimidine (Scheme 2) in 10 mL methanol for 6 h, leading to light yellow shiny particles, which were filtered, washed with methanol and dried in vacuum.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 23906-13-0, 2-Hydrazinyl-4,6-dimethylpyrimidine.

Reference:
Article; Makhal, Subhash Chandra; Bhattacharyya, Arghyadeep; Ghosh, Soumen; Guchhait, Nikhil; Journal of Photochemistry and Photobiology A: Chemistry; vol. 358; (2018); p. 138 – 146;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Synthetic Route of 23906-13-0 ,Some common heterocyclic compound, 23906-13-0, molecular formula is C6H10N4, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

Step 3: Synthesis of 3-{1-[(4, 6-Dimethyl-pyrimidin-2-yl)-hydrazono]-ethyl}-chromen-2-one: 0.19g of 1 (~1mM) was dissolved in 20ml ethanol and stirred rapidly with mild heating. To it was added 0.14g (~1mM) of 2 in portions along with introduction of a drop of glacial acetic acid. The solution was brought to reflux and continued for 6h, followed by cooling to obtain a bright yellow precipitate which was filtered under suction, washed with cold ethanol and dried under vacuum overnight. The product so obtained was characterized by 1H NMR, 13C NMR, Mass spectrometry and IR analysis. Yield: 68%. IR/cm-1 (ESI, Fig. S1): 3419.82, 1727.32, 1593.99, 1570.18, 1552.36; 1H NMR (ESI, Fig. S2) (300MHz, d6-DMSO, TMS): 10.070 (-NH, s, 1H), 8.130 (Ar-H, s, 1H), 7.850 (Ar-H, d, 1H), 7.618 (Ar-H, s, 1H), 7.428 (Ar-H, d, 1H), 7.366-7.438 ( Ar-H, m, 2H), 6.657 (Py-H, s, 1H), 2.290 (CH3-H, s, 6H), 2.229 (CH3-H, s, 3H); 13C NMR (ESI, Fig. S3) (300MHz, d6-DMSO, TMS): 167.79, 160.63, 160.00, 145.37, 141.06, 132.44, 129.43, 128.00, 125.15, 119.45, 116.41, 112.75, 23.88, 16.13; ESI-MS (ESI, Fig. S4): 309.1299, 331.1117 calculated for M+H+: 309.13 and M+Na+: 331.12.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 23906-13-0, 2-Hydrazinyl-4,6-dimethylpyrimidine, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Bhattacharyya, Arghyadeep; Ghosh, Soumen; Makhal, Subhash Chandra; Guchhait, Nikhil; Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy; vol. 183; (2017); p. 306 – 311;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.23906-13-0, name is 2-Hydrazinyl-4,6-dimethylpyrimidine, molecular formula is C6H10N4, molecular weight is 138.17, as common compound, the synthetic route is as follows.COA of Formula: C6H10N4

General procedure: To a solution of 0.2 g (3.6 mmol) of potassium hydroxide in 20 mL of ethanol was added successively 0.5 g (3.6 mmol) of hydrazine 5 and 3.6 mmol of an appropriate 3-aryl-1-phenyl-2-propen-1-one 4a-4d. The mixture was boiled for 2 h and cooled to room temperature. The separated precipitate was filtered off, washed with a minimal quantity of ethanol cooled to 5C, recrystallized from an appropriate solvent or mixture of solvents, and dried to a constant weight. Further physicochemical and spectral characteristics are listed for the products purified by crystallization.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,23906-13-0, 2-Hydrazinyl-4,6-dimethylpyrimidine, and friends who are interested can also refer to it.

Reference:
Article; Erkin; Yuzikhin; Krutikov; Russian Journal of Organic Chemistry; vol. 52; 8; (2016); p. 1173 – 1178; Zh. Org. Khim.; vol. 52; 8; (2016); p. 1181 – 1185;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 23906-13-0, name is 2-Hydrazinyl-4,6-dimethylpyrimidine, the common compound, a new synthetic route is introduced below. Recommanded Product: 23906-13-0

A mixture of 2-hydrazinyl-4,6-dimethylpyrimidine (500 mg, 3.62 mmol) and 3- aminocrotononitrile (312 mg, 3.80 mmol) in ethanol (10 mL) was heated at reflux for 3 h and was then concentrated in vacuo. The crude product was recrystallized from methanol to afford 800 mg of l-(4,6-dimethylpyrimidin-2-yl)-3-methyl-lH-pyrazol-5-amine as a pale brown solid. Yield: 90%; m/z (ESI+) 226 (MNa+), 204 (MH+).

The synthetic route of 23906-13-0 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; PROTEOSTASIS THERAPEUTICS, INC.; TAIT, Bradley; POWELL, Noel, A.; CULLEN, Matthew; WO2012/154880; (2012); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia