Adding a certain compound to certain chemical reactions, such as: 25902-86-7, 2-Methoxypyrimidin-4(1H)-one, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 25902-86-7, blongs to pyrimidines compound. Safety of 2-Methoxypyrimidin-4(1H)-one
A mixture of 18 g (0.0779 m) of the 2-methoxypyrimidinone, 12.23 g (0.0779 m) of alpha-furylmethylthioethylamine and 50 ml of toluene was heated at reflux for 12 hours. Toluene (100 ml) was added to the cooled reaction mixture. The separated solid was washed with ethyl acetate and dried to give 20.69 g (74%) of 2-[[2-[(2-furylmethyl)thio]ethyl]amino]-5-[(6-methyl-3-pyridinyl)methyl]-4-(1H)-pyrimidinone. Recrystallization from isopropanol-water gave 14.51 g (52%), m.p. 147-152, of purified compound. Anal. Calcd. for C18 H20 N4 O2 S: C, 60.25; H, 5.65; N, 15.71; S, 8.99. Found: C, 60.29; H, 5.33; N, 15.43; S, 8.50.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,25902-86-7, its application will become more common.
Reference:
Patent; Smithkline Beckman Corporation; US4352933; (1982); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia