Category: 39083-15-3

Iodocyclization of 2-(allylthio)-4(3H)-pyrimidinones was written by Kim, D. G.;Shmygarev, V. I.. And the article was included in Khimiya Geterotsiklicheskikh Soedinenii in 1995.Application of 39083-15-3 The following contents are mentioned in the article:

The title reaction gave thiazolopyrimidinium triiodides (I; R¹ = R² = H; R¹ = H, R² = Me; R¹ = Et, R² = Me). This study involved multiple reactions and reactants, such as 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3Application of 39083-15-3).

5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3) belongs to pyrimidine derivatives. The pyrimidine derivatives can easily interact with enzymes, genetic materials, and bio components within the cell. We all know its importance to life – pyrimidine and purine bases are included in the structure of DNA and RNA.Application of 39083-15-3

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Microwave promoted efficient synthesis of substituted uracils and thiouracils under solvent-free conditions was written by Mojtahedi, Mohammad M.;Saidi, Mohammad R.;Shirzi, Jafar S.;Bolourtchian, Mohammad. And the article was included in Synthetic Communications in 2002.Related Products of 39083-15-3 The following contents are mentioned in the article:

Several substituted uracils and thiouracils were synthesized in good yields by one-pot condensation reaction of Me or Et β-ketoesters and urea (or thiourea) in solvent-free conditions under microwave irradiation and in short time. This study involved multiple reactions and reactants, such as 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3Related Products of 39083-15-3).

5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3) belongs to pyrimidine derivatives. The pyrimidine nitrogenous bases are derived from the organic compound pyrimidine through the addition of various functional groups. Drugs having the pyrimidine motif have manifested to exhibit gratifying biological activity like anticancer, antiviral, anti-inflammatory, antibacterial, and antihypertensive activities.Related Products of 39083-15-3

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Kinetics of the reaction of 2-thiouracil derivatives with chloroacetic acid amides was written by Jasinskas, L.;Urbonas, A.;Dienyte, J.. And the article was included in Lietuvos TSR Aukstuju Mokyklu Mokslo Darbai, Chemija ir Chemine Technologija in 1971.Application In Synthesis of 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one The following contents are mentioned in the article:

Rate constants and activation energies were determined for the reaction of 2-thiouracil anions (I; R = Me, NH2, CO2Bu; R1 = H, Me, Et) with ClCH2COR2 (R2 = NHPh, NEt2, morpholino, NHC6H4NO2-m). The reaction occurred by an SN2 mechanism. This study involved multiple reactions and reactants, such as 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3Application In Synthesis of 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one).

5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3) belongs to pyrimidine derivatives. Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine. Pyrimidine derivatives have been used in a wide variety of pharmaceuticals including general anesthetics, anti-epilepsy medication, anti-malaria medication, drugs for treating high blood pressure, and HIV medication.Application In Synthesis of 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Synthesis and Functionalization of 5-Alkyl-6-methyl-2-thiouracils was written by Babushkina, A. A.;Egorov, D. M.;Kaskevich, K. I.. And the article was included in Russian Journal of General Chemistry in 2020.Synthetic Route of C7H10N2OS The following contents are mentioned in the article:

Number of 5-alkyl-6-methyl-2-thiouracils were obtained, the further introduction of which into the reaction with dialkyl chloroethynylphosphonates afforded a series of new dialkyl (6-alkyl-5-oxo-7-methyl-5H-thiazolo[3,2-a]pyrimidin- 3-yl)phosphonates. This study involved multiple reactions and reactants, such as 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3Synthetic Route of C7H10N2OS).

5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3) belongs to pyrimidine derivatives. Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine. Drugs having the pyrimidine motif have manifested to exhibit gratifying biological activity like anticancer, antiviral, anti-inflammatory, antibacterial, and antihypertensive activities.Synthetic Route of C7H10N2OS

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Alkylated derivatives of uracil. VI. Synthesis and properties of 5,6-oligomethyleneuracils was written by Frass, Elzbieta;Draminski, Marcin;Fiszer, Bernard. And the article was included in Roczniki Chemii in 1974.Synthetic Route of C7H10N2OS The following contents are mentioned in the article:

Reaction of β-keto esters and thiourea gave I (n = 1, 2, 3; X = S) and II (R = Me, Et; R1 = Me, Et, Pr; X = S) I (X = S) were converted to I (X = O) by heating with 10% ClCH2CO2H. Irradiation of I and II with a low pressure lamp gave only 10% yields of products. This study involved multiple reactions and reactants, such as 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3Synthetic Route of C7H10N2OS).

5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3) belongs to pyrimidine derivatives. Pyrimidines are isomeric with two other forms of diazines: pyridazine, with the nitrogen atoms in the 1 and 2 positions; and pyrazine, with the nitrogen atoms in the 1 and 4 positions. Pyrimidine derivatives also play an important role in drug development, either in concert with other compounds or on their own.Synthetic Route of C7H10N2OS

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

(2,3-Dibromopropyl)sulfonylarenes in S,N-Tandem Heterocyclizations. A New Synthesis of Thiazolopyrimidines was written by Shklyarenko, A. A.;Chernitsa, B. V.;Yakovlev, V. V.. And the article was included in Russian Journal of Organic Chemistry in 2005.HPLC of Formula: 39083-15-3 The following contents are mentioned in the article:

A new method for the synthesis of dihydrothiazolo[3,2-a]pyrimidinones, e.g. I, via S,N-tandem heterocyclization/alkylation of aryl 2,3-dibromopropyl sulfones and 2-thiouracils, is reported. The absence of isomeric products in the reaction mixtures indicates high chemo- and regioselectivity of this tandem reaction and suggests a concerted mechanism. This study involved multiple reactions and reactants, such as 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3HPLC of Formula: 39083-15-3).

5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3) belongs to pyrimidine derivatives. Pyrimidine also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. As nucleotides in DNA and RNA, pyrimidine nucleotide derivatives have a wide range of biological applications. For example, pyrimidine derivatives are useful in DNA repair studies involving cancer and epigenetics.HPLC of Formula: 39083-15-3

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Synthesis and antitumor activity of 2-alkanesulfinyl (or alkanesulfonyl)-7-methyl-5H-1,3,4-thiadiazolo[3,2-a]pyrimidin-5-ones was written by Suiko, Masahito;Maekawa, Kazuyuki. And the article was included in Agricultural and Biological Chemistry in 1977.Name: 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one The following contents are mentioned in the article:

The title compounds, I and II, were synthesized by m-chloroperbenzoic acid oxidation of the corresponding thioethers produced by coupling of alkylthio-thiadiazoles with Et acetoacetate. Compounds with electrophilic substituents, such as alkylsulfoxide or alkylsulfone, at the 2-position had a strong repressing effect on the propagation of Ehrlich ascites tumor cells. This study involved multiple reactions and reactants, such as 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3Name: 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one).

5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3) belongs to pyrimidine derivatives. Heterocyclic compounds bearing the pyrimidine core are of tremendous interest as they constitute an important class of natural and synthetic compounds exhibiting diverse useful biological activities that hold attractive potential for clinical translation as therapeutic agents in alleviation of a myriad of diseases. Pyrimidine derivatives have been used in a wide variety of pharmaceuticals including general anesthetics, anti-epilepsy medication, anti-malaria medication, drugs for treating high blood pressure, and HIV medication.Name: 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

H₂-Antihistaminics, XVIII. 5,6-Alkyl-4-pyrimidones with H₂-antihistaminic activity was written by Spengler, Jan Peter;Schunack, Walter. And the article was included in Archiv der Pharmazie (Weinheim, Germany) in 1984.Synthetic Route of C7H10N2OS The following contents are mentioned in the article:

2-[[2-[[(5-Methyl-4-imidazolyl)methyl]thio]ethyl]amino]-4(3H)-pyrimidinones (I)(R = H or Me through octyl, R¹ = H; R = H or Me through pentyl, R¹ = Me; R = H, R¹ = Et) were prepared The antihistaminic activity of I increased with chain length, reached a maximum (almost 10 times that of metiamide) for R = Bu, R¹ = H, and slowly declined thereafter. This study involved multiple reactions and reactants, such as 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3Synthetic Route of C7H10N2OS).

5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3) belongs to pyrimidine derivatives. Heterocyclic compounds bearing the pyrimidine core are of tremendous interest as they constitute an important class of natural and synthetic compounds exhibiting diverse useful biological activities that hold attractive potential for clinical translation as therapeutic agents in alleviation of a myriad of diseases. Therapy for fungal infections is based mainly on four classes of antifungals: azoles, echinocandins, polyenes, and pyrimidine analogs.Synthetic Route of C7H10N2OS

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Solid phase synthesis of 5,6-disubstituted pyrimidinone and pyrimidindione derivatives was written by Parlato, Maria cristina;Mugnaini, Claudia;Renzulli, Michela Lucia;Corelli, Federico;Botta, Maurizio. And the article was included in ARKIVOC (Gainesville, FL, United States) in 2004.Category: pyrimidines The following contents are mentioned in the article:

Solid phase synthesis of 5,6-disubstituted pyrimidinone and pyrimidindione derivatives, e.g. I and II, were prepared, in 88 and 85% yield, by condensing polymer bound thiouronium salts with β-ketoesters, e.g. Et acetoacetate, and cleavage of the product with TFA and Oxone/H₂O/dioxane, resp. Combinatorial libraries of pyrimidindiones, 2-thiopyrimidinones, and 2-methoxypyrimidinones were generated by using a Syncore Reactor. This study involved multiple reactions and reactants, such as 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3Category: pyrimidines).

5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3) belongs to pyrimidine derivatives. Pyrimidines are isomeric with two other forms of diazines: pyridazine, with the nitrogen atoms in the 1 and 2 positions; and pyrazine, with the nitrogen atoms in the 1 and 4 positions. A Cu-catalyzed and 4-HO-TEMPO-mediated [3 + 3] annulation of commercially available amidines with saturated ketones enables an efficient and facile synthesis of structurally important pyrimidines via a cascade reaction of oxidative dehydrogenation/annulation/oxidative aromatization.Category: pyrimidines

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Synthesis and properties of 2-(styrylthio)pyrimidin-6(1H)-ones was written by Kim, D. G.;Shmygarev, V. I.;Kharlampieva, E. P.;Vorob’ev, D. V.. And the article was included in Russian Journal of Organic Chemistry in 1997.Reference of 39083-15-3 The following contents are mentioned in the article:

Addition of 2-thioxo-1,2,3,4-tetrahydro-4-pyrimidinone derivatives (i.e. 2-thiouracil derivatives) to phenylacetylene in superbasic medium (DMSO-KOH) proceeds regio- and stereoselectively with formation of 2-(styrylthio)-6(1H)-pyrimidinone derivatives. Alkylation of these products with allyl bromide in alk. medium occurs at the N¹ and oxygen atoms. 1-Allyl-2-(styrylthio)-6(1H)-pyrimidinone undergoes intramol. cyclization into oxazolo[3,2-c]pyrimidine system on treatment with iodine. This study involved multiple reactions and reactants, such as 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3Reference of 39083-15-3).

5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3) belongs to pyrimidine derivatives. Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine. Drugs having the pyrimidine motif have manifested to exhibit gratifying biological activity like anticancer, antiviral, anti-inflammatory, antibacterial, and antihypertensive activities.Reference of 39083-15-3

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia