Category: 53112-28-0

With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.53112-28-0, name is 4,6-Dimethyl-N-phenyl-2-pyrimidinamine, molecular formula is C12H13N3, molecular weight is 199.2517, as common compound, the synthetic route is as follows.Safety of 4,6-Dimethyl-N-phenyl-2-pyrimidinamine

EXAMPLE 5 Methylsulphonyl isocyanate (3.15 g) was added dropwise to a solution of 2-anilino-4,6-dimethylpyrimidine (3.98 g) in toluene (40 ml). The mixture was then stirred for 2 hours at room temperature. The solid was separated and dried in vacuo, to give 1-(4,6-dimethylpyrimidine-2-yl)-3-methylsulphonyl-1-phenylurea, m.p. 186-192. (Compound 5).

At the same time, in my other blogs, there are other synthetic methods of this type of compound,53112-28-0, 4,6-Dimethyl-N-phenyl-2-pyrimidinamine, and friends who are interested can also refer to it.

Reference:
Patent; Schering Agrochemicals Ltd.; US4783459; (1988); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Reference of 53112-28-0, Adding some certain compound to certain chemical reactions, such as: 53112-28-0, name is 4,6-Dimethyl-N-phenyl-2-pyrimidinamine,molecular formula is C12H13N3, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 53112-28-0.

EXAMPLE 3 2-Anilino-4,6-dimethylpyrimidine (10 g) was added to formic-acetic anhydride (prepared from formic acid (5 ml) and acetic anydride (12 ml)) and the mixture heated gently to 40 to give a clear solution. After standing for 4 days, a crystalline solid separated and toluene was added to give a clear solution again. The mixture was evaporated to dryness, more toluene added and reevaporated. The product was recrystallized from ethyl acetate/light petroleum to give N-(4,6-dimethylpyrimidin-2-yl)-formanilide, m.p. 134-5. (Compound 3).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 53112-28-0, 4,6-Dimethyl-N-phenyl-2-pyrimidinamine, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Schering Agrochemicals Ltd.; US4783459; (1988); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Related Products of 53112-28-0, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 53112-28-0, name is 4,6-Dimethyl-N-phenyl-2-pyrimidinamine. A new synthetic method of this compound is introduced below.

Preparation of the Co-Crystal Comprising Pyrimethanil and Dithiine Tetracarboximide of the Formula (I). Preparation 83 mg of pyrimethanil and 117 mg of dithiine tetracarboximide of the formula (I) are suspended in 2 mL of water or in a mixture of water and polar organic solvent. The suspension solution is stirred until a red powder is obtained (pyrimethanil is a white powder, dithiine tetracarboximide of the formula (I) is a blue powder). The solid material is separated by filtration and dried at 25 C. for 12 hours. The corresponding PXRD pattern and DSC trace are shown in FIG. 1 and in FIG. 3, respectively.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,53112-28-0, its application will become more common.

Reference:
Patent; BASF SE; BRATZ, Matthias; CHIODO, Tiziana; KOULELIS, Dennis; MERTOGLU, Murat; (16 pag.)US2016/15034; (2016); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 53112-28-0, name is 4,6-Dimethyl-N-phenyl-2-pyrimidinamine, the common compound, a new synthetic route is introduced below. 53112-28-0

EXAMPLE 5 Preparation of 4,6-dimethyl-2-(N-nitrosoanilino)pyrimidine (Compound 8) To a solution of 2.0 g of 2-anilino-4,6-dimethylpyrimidine in 15 ml of acetic acid was added dropwise a solution of 1.4 g of sodium nitrite in 10 ml of water. After 30 minute’s stirring, 50 ml of water was added to the mixture. The resulting crystals were collected by filtration and dried. Recrystallization from ethanol afforded 1.7 g (yield: 74%) of 4,6-dimethyl-2-(N-nitrosoanilino)pyrimidine having a melting point of 117 – 121 C.

Statistics shows that 53112-28-0 is playing an increasingly important role. we look forward to future research findings about 4,6-Dimethyl-N-phenyl-2-pyrimidinamine.

Reference:
Patent; KUMIAI CHEMICAL INDUSTRY CO., LTD.; IHARA CHEMICAL INDUSTRY Co., Ltd.; EP270111; (1991); B1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia