Category: 5334-35-0

Related Products of 5334-35-0, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 5334-35-0, name is 6-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4(7H)-one. This compound has unique chemical properties. The synthetic route is as follows.

Example 110 1 -methyl-6-(4-methylsulfonyl- 1 -piperidyl)-5H-pyrazolo[3 4-d]pyrimidin-4-one (1-141) The title compound was prepared by condensation (DIPEA/EtOH) of 4-methylsulfonyl- piperidine (CASRN 290328-55-1) and Intermediate A: 1H-NMR (400MHz, DMSO-i ) delta ppm 10.97 (s, 1H), 7.77 (s, 1H), 4.49 (d, J = 16.0Hz, 2H), 3.73 (s, 3H), 3.43-3.35 (m, 1H), 3.03-2.95 (m, 5H), 2.09 (d, J = 11.2Hz, 2H), 1.65-1.55 (m, 2H).

According to the analysis of related databases, 5334-35-0, the application of this compound in the production field has become more and more popular.

Reference:
Patent; F. HOFFMANN-LA ROCHE AG; HOFFMANN-LA ROCHE INC.; FENG, Jianwen; HAYNES, Nancy-Ellen; HERMANN, Johannes Cornelius; KIM, Kyungjin; LIU, Jin-Jun; SCOTT, Nathan Robert; YI, Lin; ZAK, Mark; ZHAO, Guiling; WO2013/182546; (2013); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Electric Literature of 5334-35-0 ,Some common heterocyclic compound, 5334-35-0, molecular formula is C6H5ClN4O, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

Example 109 l-methyl-6-(4-methylsulfonylpiperazin-l-yl)-5H-pyrazolo[3 4-d]pyrimidin-4-one (1-142) CASE 30893 step 2 The title compound was prepared by condensation (DIPEA/EtOH) of l-(methylsulfonyl)- piperazine (CASRN 55776-43-2) and Intermediate A: -NMR (400MHz, DMSO-i ) delta ppm 11.07 (s, 1H), 7.80 (s, 1H), 3.78-3.74 (m, 7H), 3.18 (t, J = 4.4 Hz, 4H), 2.91 (s, 3H).

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,5334-35-0, its application will become more common.

Reference:
Patent; F. HOFFMANN-LA ROCHE AG; HOFFMANN-LA ROCHE INC.; FENG, Jianwen; HAYNES, Nancy-Ellen; HERMANN, Johannes Cornelius; KIM, Kyungjin; LIU, Jin-Jun; SCOTT, Nathan Robert; YI, Lin; ZAK, Mark; ZHAO, Guiling; WO2013/182546; (2013); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia