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Trilleras, Jorge et al. published their research in Acta Crystallographica, Section C: Crystal Structure Communications in 2008 | CAS: 54030-56-7

6-Amino-3-methyl-2-(methylthio)pyrimidin-4(3H)-one (cas: 54030-56-7) belongs to pyrimidine derivatives. The aromatic compound pyrimidine, and its derivatives, are ubiquitous in nature. They are found in nucleic acids, vitamins, amino acids, antibiotics, alkaloids, and a variety of toxins. Drugs having the pyrimidine motif have manifested to exhibit gratifying biological activity like anticancer, antiviral, anti-inflammatory, antibacterial, and antihypertensive activities.Category: pyrimidines

Four products from the cyanoacetylation of pyrimidines: hydrogen-bonded dimers, π-stacked hydrogen-bonded chains and hydrogen-bonded chains of edge-fused rings was written by Trilleras, Jorge;Low, John N.;Cobo, Justo;Marchal, Antonio;Glidewell, Christopher. And the article was included in Acta Crystallographica, Section C: Crystal Structure Communications in 2008.Category: pyrimidines This article mentions the following:

The mols. of 2-[6-amino-3-methyl-2-(methylsulfanyl)-4-oxo-3,4-dihydropyrimidin-5-ylcarbonyl]acetonitrile, C₉H₁₀N₄O₂S, (I), are linked in pairs by N-H···O hydrogen bonds to form cyclic centrosym. R₂²(4) dimers. Similar dimers formed by 2-(6-amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-ylcarbonyl)acetonitrile, C₉H₁₀N₄O₃, (II), are reinforced by paired N-H···N hydrogen bonds and linked into chains of rings by C-H···O hydrogen bonds. The mols. of 2-cyano-N-[6-methoxy-2-(methylsulfanyl)pyrimidin-4-yl]acetamide, C₉H₁₀N₄O₂S, (III), are linked into simple C(6) chains by an N-H···N hydrogen bond, and the chains are weakly linked into sheets by a π-π stacking interaction. A combination of one two-center N-H···N hydrogen bond and one three-center C-H···(N,O) hydrogen bond links the mols. of 2-cyano-N-[6-chloro-2-(methylsulfanyl)pyrimidin-4-yl]acetamide, C₈H₇ClN₄OS, (IV), into a chain of alternating edge-fused R₂¹(6) and R₁²(6) rings. The crystal structures reported in this study, and those of some related examples from the recent literature, show a wide variation in hydrogen-bonded aggregation consequent upon rather small changes in mol. constitution. In the experiment, the researchers used many compounds, for example, 6-Amino-3-methyl-2-(methylthio)pyrimidin-4(3H)-one (cas: 54030-56-7Category: pyrimidines).

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Nogueras Montiel, M. et al. published their research in Anales de Quimica, Serie C: Quimica Organica y Bioquimica in 1984 | CAS: 54030-56-7

6-Amino-3-methyl-2-(methylthio)pyrimidin-4(3H)-one (cas: 54030-56-7) belongs to pyrimidine derivatives. The pyrimidine nitrogenous bases are derived from the organic compound pyrimidine through the addition of various functional groups. As nucleotides in DNA and RNA, pyrimidine nucleotide derivatives have a wide range of biological applications. For example, pyrimidine derivatives are useful in DNA repair studies involving cancer and epigenetics.Formula: C6H9N3OS

Aminopyrimidines and derivatives. XIV. Preparation and study of 5-amino-4-(glycosylamino)-2-methoxy-(and 2-(methylthio))-6-oxopyrimidines was written by Nogueras Montiel, M.;Sanchez Rodrigo, A.;Asenjo Asenjo, R.;Melgarejo Sampedro, M.;Rodriguez Alonso, M.;Rodriguez Melgarejo, C.. And the article was included in Anales de Quimica, Serie C: Quimica Organica y Bioquimica in 1984.Formula: C6H9N3OS This article mentions the following:

(Glycosylamino)pyrimidinones (I; R = H, Me; R¹ = H; R² = H, CH₂OH; Z = O, S; 7 compounds) on treatment with NaNO₂ in AcOH or HCl gave the corresponding 5-nitroso compounds (I; R¹ = NO), which on reduction with (NH₄)₂S gave the title compounds (I; R¹ = NH₂). In the experiment, the researchers used many compounds, for example, 6-Amino-3-methyl-2-(methylthio)pyrimidin-4(3H)-one (cas: 54030-56-7Formula: C6H9N3OS).