Category: 56621-93-3

Shkurko, O. P. published the artcileEquilibrium NH-acidity of substituted aminopyrimidines, SDS of cas: 56621-93-3, the publication is Zhurnal Organicheskoi Khimii (1981), 17(2), 312-17, database is CAplus.

The transmetalation method was used to determine the NH acidity (pK) of thirty-nine 2-, 4-, and 5-aminopyrimidines; the pK values ranged from 17.7 for 5-nitro-2-pyrimidinamine to 30.2 for 2-(dimethylamino)-5-pyrimidinamine. Comparison with the pK of aniline showed that the ring N atoms had an acidifying effect in the order 4-aza ≫ 2-aza > 3-aza. LFER of the pK vs. NMR chem. shifts, and inductive or resonance substituent constants were described.

Zhurnal Organicheskoi Khimii published new progress about 56621-93-3. 56621-93-3 belongs to pyrimidines, auxiliary class Pyrimidine,Nitrile,Amine, name is 5-Aminopyrimidine-2-carbonitrile, and the molecular formula is C17H37NO3, SDS of cas: 56621-93-3.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/Pyrimidine,
Pyrimidine – Wikipedia

Shkurko, O. P. published the artcileNMR spectra of pyrimidines. Effect of substituents on a chemical shift of amino group protons of p-substituted 2- and 5-aminopyrimidines and anilines, Product Details of C5H4N4, the publication is Khimiya Geterotsiklicheskikh Soedinenii (1979), 1683-6, database is CAplus.

NMR data for 4-substituted anilines, 5-substituted 2-aminopyrimidines, and 2-substituted 5-aminopyrimidines were subjected to correlation anal. The inductive effects were transmitted approx. equally through the benzene and pyrimidine rings. The conjugation effects were transmitted with equal efficiency through the benzene ring and from position 5 to position 2 of the pyrimidine ring; transmission from position 2 to position 5 of the pyrimidine ring was somewhat more efficient.

Khimiya Geterotsiklicheskikh Soedinenii published new progress about 56621-93-3. 56621-93-3 belongs to pyrimidines, auxiliary class Pyrimidine,Nitrile,Amine, name is 5-Aminopyrimidine-2-carbonitrile, and the molecular formula is C40H35N7O8, Product Details of C5H4N4.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/Pyrimidine,
Pyrimidine – Wikipedia

Mikhaleva, M. A. published the artcileSynthesis of Schiff bases of 2-substituted 5-aminopyrimidines and their mesomorphic properties, Computed Properties of 56621-93-3, the publication is Khimiya Geterotsiklicheskikh Soedinenii (1982), 1545-52, database is CAplus.

Schiff bases I (R = MeO, BuO, Me, Cl, CN, p-MeOC₆H₄, p-BuOC₆H₄, p-C₆H₁₃OC₆H₄, Ph, p-BrC₆H₄; R¹ = alkoxy, NO₂) were prepared in 32-100% yields by condensation of 4-R¹C₆H₄CHO with the corresponding aminopyrimidine and the liquid crystal properties (anisotropic dielec. permeability) of I (R, R¹ = MeO, C₆H₁₃O; BuO, C₈H₁₇O; Cl, C₉H₁₉O; CN, BuO; p-C₆H₁₃OC₆H₄, C₆H₁₃O) were determined

Khimiya Geterotsiklicheskikh Soedinenii published new progress about 56621-93-3. 56621-93-3 belongs to pyrimidines, auxiliary class Pyrimidine,Nitrile,Amine, name is 5-Aminopyrimidine-2-carbonitrile, and the molecular formula is C5H4N4, Computed Properties of 56621-93-3.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/Pyrimidine,
Pyrimidine – Wikipedia