Adding a certain compound to certain chemical reactions, such as: 5734-64-5, 4-Chloro-6-methoxypyrimidin-2-amine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Application In Synthesis of 4-Chloro-6-methoxypyrimidin-2-amine, blongs to pyrimidines compound. Application In Synthesis of 4-Chloro-6-methoxypyrimidin-2-amine
1.6 g (0.01 mol) of 2-amino-4-chloro-6-methoxypyrimidine are dissolved in 30 ml of dichloromethane, and 2.7 g (0.01 mol) of 1-pyrrolidinosulfonylethylsulfonyl isocyanate (Example 3b) in 30 ml of dichloromethane are added dropwise at room temperature. After the mixture has been stirred for 3 hours at room temperature, the organic phase is washed with 2N HCl and water, dried and evaporated. Trituration of the crude product with diethyl ether gives 30 g (70% of theory) of 3-(4-chloro-6-methoxypyrimidin-2-yl)-1-(1-pyrrolidinosulfonylethylsulfonyl)urea of melting point 158-160 C.
The synthetic route of 5734-64-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Hoechst Aktiengesellschaft; US5223017; (1993); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia