In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 7234-25-5, name is Ethyl 4-Methyl-2-(methylthio)-5-pyrimidinecarboxylate, the common compound, a new synthetic route is introduced below. Recommanded Product: 7234-25-5
b. Preparation of 4-((E)-2-Dimethylamino-vinyl)-2-methylsulfanyl-pyrimidine-5- carboxylic acid ethyl ester 5.4-Methyl-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester 3 (18.0 g, 84.8 mmol) was dissolved in DMF (5OmL), N.N-Dimethylformamiddimethylacetal (22.5 ml_, 170 mmol) and stirred at reflux for 3 hours. Then mixture was concentrated, the residue was dissolved in TCM, washed with water, dried, filtered, and concentrated. The prod- uct was purified by crystallization from ether to yield in a colorless solid (14.0 g, 52.5 mmol, 62 %).
The synthetic route of 7234-25-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; MERCK PATENT GMBH; SCHIEMANN, Kai; SCHULTZ, Melanie; STAEHLE, Wolfgang; KOBER, Ingo; WIENKE, Dirk; KRIER, Mireille; WO2010/63352; (2010); A1;,
Pyrimidine | C4H4N2 – PubChem,
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