Category: 7431-45-0

Adding a certain compound to certain chemical reactions, such as: 7431-45-0, 2-Phenylpyrimidine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 7431-45-0, blongs to pyrimidines compound. category: pyrimidines

General procedure: [Cp*RhCl2]2 (2.5 mol %), Cu(OTf)2 (5 mol %), 1a (0.2 mmol), 2a (0.6 mmol, 3 equiv) and DCE (2 mL) were added to a test tube. The reaction mixture was stirred at 90 oC for 12 h. After that, the solvent was removed under reduced pressure and the residue was purified by silica gel chromatography using PE/EA (5:1) to afford the title compound 4a.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,7431-45-0, its application will become more common.

Reference:
Article; Jin, Chen; Wang, Guimin; Yang, Xueyan; Zhu, Weiliang; Yang, Yaxi; Tetrahedron Letters; vol. 59; 21; (2018); p. 2042 – 2045;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Reference of 7431-45-0, Adding some certain compound to certain chemical reactions, such as: 7431-45-0, name is 2-Phenylpyrimidine,molecular formula is C10H8N2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 7431-45-0.

General procedure: To a dried Schlenk tube was equipped with a magnetic stirbar. [Cp*RhCl2]2 (0.005 mmol, 2.5 mol %, 3.1 mg), AgSbF6 (0.03 mmol, 15 mol %,10.3 mg), substrate 1 (0.2 mmol or 0.4 mmol), HOAc (1 ml), substrate 2 (0.24 mmolor 0.2 mmol) were added sequentially under argon. The tube was stirred at roomtemperature or 80 C for 12 h. After completion of the reaction, the mixture wasdiluted with EtOAc (10 mL), filtered through a short pad of silica gel and washedwith EtOAc (30 mL). The filtrate was pre-absorbed on silica gel and concentrated byrotary evaporation. The crude product was purified by flash silica gel (300-400 mesh)chromatography to afford the desired products product 3.

According to the analysis of related databases, 7431-45-0, the application of this compound in the production field has become more and more popular.

Reference:
Article; Duan, Chang-Lin; Liu, Xing-Yu; Tan, Yun-Xuan; Ding, Rui; Yang, Shiping; Tian, Ping; Lin, Guo-Qiang; Synlett; vol. 30; 8; (2019); p. 932 – 938;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Application of 7431-45-0, Adding some certain compound to certain chemical reactions, such as: 7431-45-0, name is 2-Phenylpyrimidine,molecular formula is C10H8N2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 7431-45-0.

General procedure: In a Schlenk tube, a solution of R3In (0.375 mmol, ~0.3M en THF) and the arylpyridine (0.25 mmol)were successively added to a solution of Rh(PPh3)3Cl (24 mg, 0.025 mmol) in chlorobenzene (20 mL).The mixture was stirred at 120 C during 48 h, and the reaction quenched by addition of dropsof MeOH. The solvent was evaporated and CHCl3 (25 mL) was added. The organic phase waswashed with aq. NH3 (5%, 15 mL), dried, filtered, and concentrated. The crude was purified by flash chromatography (Et2O/hexane) affording, after concentration and drying, the cross-coupling products.

According to the analysis of related databases, 7431-45-0, the application of this compound in the production field has become more and more popular.

Reference:
Article; Riveiros, Ricardo; Tato, Ruben; Sestelo, Jose Perez; Sarandeses, Luis A; Molecules; vol. 23; 7; (2018);,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia