2,4-Diamino-6-piperidinyl- and 6-piperazinylpyrimidine 3-oxides, new analogs of minoxidil was written by Catto, A.; Lo Verde, G.; Luca, C.; Graziani, G.; Nardi, D.; Casadio, S.. And the article was included in Bollettino Chimico Farmaceutico on January 31,1982.HPLC of Formula: 35139-67-4 The following contents are mentioned in the article:
Title compounds [I; R = Ph, 1-substituted 4-piperidinyl, 1-piperidinyl, CONH2, PhCONH; R1 = OH, H; and RR1 = (CH2)5, SCH2CH2S, OZO (Z = linear or branched alkylene)] and (II; R2 = H, Me, substituted pyrimidinyl, 2-MeOC6H4, 3-ClC6H4, 2-pyridyl) were prepared from 6-chloro-2,4-pyrimidinediamine 3-oxide (III) and III·3-ClC6H4CO2H; I and II exhibited antihypertensive activity. III was treated with 4-phenyl-4-piperidinol to give I (R = Ph, R1 = OH). This study involved multiple reactions and reactants, such as 2,6-Diamino-4-chloropyrimidine-1-oxide (cas: 35139-67-4HPLC of Formula: 35139-67-4).
2,6-Diamino-4-chloropyrimidine-1-oxide (cas: 35139-67-4) belongs to pyrimidine derivatives. The pyrimidine derivatives can easily interact with enzymes, genetic materials, and bio components within the cell. For example, the neurotoxin tetrodotoxin is a pyrimidine derivative. It is found in a number of species including the Japanese puffer fish, the blue-ringed octopus, and the orange-bellied newt. Tetrodotoxin prevents the transmission of nerve signals and can result in paralysis and death.HPLC of Formula: 35139-67-4
35139-67-4;2,6-Diamino-4-chloropyrimidine-1-oxide;The future of 35139-67-4;New trend of C4H5ClN4O;function of 35139-67-4