In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Synthesis of 2-ethylthioisonicotinamide, published in 1965, which mentions a compound: 148-51-6, mainly applied to , SDS of cas: 148-51-6.
2-Ethylisonicotinaldehyde diethylacetal (I), b14 125-8°, was prepared in 61% yield from EtBr 112.2, Mg 33, 2-ethyl-4-bromopyridine 62, tri-Et orthoformate 180, and NH4Cl 215 g. Hydrolysis of 15.3 g. I with 150 ml. 10% HCl gave 83% free aldehyde (II), b20 92-5°; hydrazone m. 46-8°; thiosemicarbazone m. 215-16°. Willgerodt reaction of 0.75 g. II with 0.16 g. S in 30 ml. pyridine and 20 ml. NH3 yielded 56.5% of 2-ethylthioisonicotinoylamide.
Compound(148-51-6)SDS of cas: 148-51-6 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride), if you are interested, you can check out my other related articles.
Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia