Chen, Bang-Chi; Quinlan, Sandra L.; Reid, J. Gregory; Spector, Richard H. published an article on February 19 ,1998. The article was titled 《A new thymine free synthesis of the anti-AIDS drug d4T via regio/stereo controlled β-elimination of bromoacetates》, and you may find the article in Tetrahedron Letters.Formula: C17H16N2O5 The information in the text is summarized as follows:
The anti-AIDS drug d4T was prepared without contamination of the nucleoside bond cleaved byproduct thymine from the readily available ribonucleoside 5-methyluridine. This was accomplished by using a new strategy which involved a regio/stereo controlled β-elimination of trans-bromoacetates. The experimental process involved the reaction of ((2S,5R)-5-(5-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dihydrofuran-2-yl)methyl benzoate(cas: 122567-97-9Formula: C17H16N2O5)
((2S,5R)-5-(5-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dihydrofuran-2-yl)methyl benzoate(cas: 122567-97-9) belongs to pyrimidine. Pyrimidine nucleotide derivatives have a wide range of biological applications. For example, pyrimidine derivatives are useful in DNA repair studies involving cancer and epigenetics.Formula: C17H16N2O5
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia