On November 23, 2016, Chen, Wei published a patent.Safety of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate The title of the patent was A compound niacin injection, its preparation method and application for treating human intestinal diseases. And the patent contained the following:
The compound niacin injection is prepared from: main agent 10-20, additive 6-10, and solvent 400-500 weight parts. The main agent is formulated from: nicotinic acid 6-10, berberine sulfate 2-4, or atropine sulfate 6-8, mequindox 3-5, trimethoprim lactate 12-16, and Chinese medicine extracting solution 5-7 weight parts; the additive is formulated from sodium sulfite 2-3, sodium thiosulfate 1-2, and disodium edetate 0.6-1 weight parts. The Chinese medicine extracting solution is prepared by extracting Herba Andrographis 6-8, Herba Dendrobii 4-6, Radix Et Rhizoma Rhei 3-5, and Flos Carthami 6-8 with alc. 40-50 weight parts. The preparation method includes extracting with ethanol, cooling, filtering, dialyzing, supplying solvent, and stirring well. The invented compound niacin injection can be used for treating intestinal tract diseases of human body, it has good effect for inhibiting bacteria such as escherichia coli, staphylococcus, and helicobacter in human intestinal tract, and its curative effect is better than the single preparation of each medicine, and it has reasonable formula, the used raw materials are all the efficient drugs for resisting intestinal bacteria infection, and are safe to use, and have obvious curative effect. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Safety of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate
The Article related to compound niacin injection preparation chinese medicine extract natural pharmaceutical, Pharmaceuticals: Formulation and Compounding and other aspects.Safety of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia