On March 24, 2016, Chesworth, Richard; Moradei, Oscar Miguel; Shapiro, Gideon; Jin, Lei; Babine, Robert E. published a patent.Synthetic Route of 1187830-46-1 The title of the patent was CARM1 inhibitors for treating Cancer and Metabolic disorders. And the patent contained the following:
Provided herein are compounds that are useful for inhibiting CARM1 activity. Methods of using the compounds for treating CARM1-mediated disorders are also described. The experimental process involved the reaction of 6,7-Dihydro-5H-pyrrolo[3,4-d]pyrimidine hydrochloride(cas: 1187830-46-1).Synthetic Route of 1187830-46-1
The Article related to carm1 inhibitor preparation cancer metabolic disease, Pharmacology: Effects Of Neoplasm Inhibitors and Cytotoxic Agents and other aspects.Synthetic Route of 1187830-46-1
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia