Cooper, Julian C.; Luo, Chaosheng; Kameyama, Ryohei; Van Humbeck, Jeffrey F. published an article on January 31 ,2018. The article was titled 《Combined Iron/Hydroxytriazole Dual Catalytic System for Site Selective Oxidation Adjacent to Azaheterocycles》, and you may find the article in Journal of the American Chemical Society.Safety of 5-Bromo-4-ethylpyrimidine The information in the text is summarized as follows:
This report details a new method for site-selective methylene oxidation adjacent to azaheterocycles. A dual catalysis approach, utilizing both an iron Lewis acid and an organic hydroxylamine catalyst, proved highly effective. We demonstrate that this method provides complementary selectivity to other known catalytic approaches and represents an improvement over current heterocycle-selective reactions that rely on stoichiometric activation. After reading the article, we found that the author used 5-Bromo-4-ethylpyrimidine(cas: 951884-36-9Safety of 5-Bromo-4-ethylpyrimidine)
5-Bromo-4-ethylpyrimidine(cas: 951884-36-9) is a member of pyrimidine. Pyrimidine derivatives are an important class of N-heterocycles. They are well-known for their wide spectrum of promising biological activities such as antitumors, bactericidals, and fungicidal.Safety of 5-Bromo-4-ethylpyrimidine
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia