The systematic study of pyrimidines began in 1884 with Pinner, who synthesized derivatives by condensing ethyl acetoacetate with amidines. Pinner first proposed the name “pyrimidin” in 1885. 109-12-6, formula is C4H5N3, Name is Pyrimidin-2-amine. The parent compound was first prepared by Gabriel and Colman in 1900, by conversion of barbituric acid to 2,4,6-trichloropyrimidine followed by reduction using zinc dust in hot water. COA of Formula: C4H5N3.
Cui, Hao;Tian, Yu;Zhang, Jun;Ma, Shanshan;Li, Lipin;Zuo, Wei;Zhang, Lei;Wang, Tong research published 《 Enhanced oxidation of sulfadiazine by two-stage ultrasound assisted zero-valent iron catalyzed persulfate process: Factors and pathways》, the research content is summarized as follows. The existence of sulfonamides (SAs) in water bodies leads to a series of human health problems and environmental risks. Ultrasound (US) enhanced zero-valent iron catalyzed persulfate (ZVI/PS) process is a potential approach to eliminate SAs. However, high energy consumption and large ZVI usage limited its application. In this study, a novel two-stage US-ZVI/PS process was first proposed, which reduced 35% of ZVI usage and saved 74.2% of energy consumption compared with traditional US-ZVI/PS process. The effect of introduction time and operation mode of US on sulfadiazine (SD, 20 mg L-1) degradation was first investigated. The intermittent operation method of US (60 s on/60 s off) could help controlling the releasing of Fe2+ in a reasonable range (0.37-0.56 mg L-1), which was the key reason for the high SD degradation efficiency. SO·-4, ·OH were confirmed as the key radicals for SD removal, and four degradation pathways were proposed. The initial pH of 5.0-7.0, the initial ZVI and PS doses of 0.6 mM and 1.4 mM were determined as the optimal conditions for high SD removal efficiency. Compared to other SD removal processes (traditional US/ZVI/PS, ozonation and UV-based process), two-stage US-ZVI/PS saved 68.3-98.5% energy consumption and enhanced 0.7-14.0 times degradation rate. Therefore, two-stage US-ZVI/PS system is promising and cost-effective for the removal of SD.
COA of Formula: C4H5N3, 2-Aminopyrimidine is a useful research compound. Its molecular formula is C4H5N3 and its molecular weight is 95.1 g/mol. The purity is usually 95%.
2-Aminopyrimidine is an organic compound that belongs to the group of pyridines. It has been shown to have antimicrobial, antitumor, and antiviral properties. 2-Aminopyrimidine has been used as a fungicide and herbicide in horticulture and agriculture, respectively. The molecular geometry of this molecule is octahedral with coordination geometry C2v. This chemical binds to the BCR-ABL kinase receptor and inhibits its activity by competitive inhibition of ATP binding. 2-Aminopyrimidine has been shown to have a hematologic response in vivo models and in vitro assays. It also has anti-inflammatory effects when it is taken orally or applied topically., 109-12-6.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia