A practical and cost-effective approach to polysubstituted pyrimidine derivatives via DBU mediated redox isomerization of propargyl alcohol and subsequent N-C-N fragment condensation was written by De, Rimpa;Sengupta, Utsav;Savarimuthu, Antony;Misra, Souvik;Nanda, Jayanta;Bera, Mrinal K.. And the article was included in New Journal of Chemistry in 2022.HPLC of Formula: 40230-24-8 This article mentions the following:
A straightforward, efficient yet effortless approach for the synthesis of structurally important triarylated pyrimidine derivatives has been successfully developed using secondary propargyl alc. and com. available amidines under mild basic conditions. The reaction is believed to proceed via base-mediated redox isomerization of propargyl alc. into a chalcone and a subsequent N-C-N fragment condensation reaction with the in situ generated chalcone. The procedure may be successfully employed to generate a large array of polysubstituted pyrimidine derivatives from milligram to multigram scale. In the experiment, the researchers used many compounds, for example, 4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8HPLC of Formula: 40230-24-8).
4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8) belongs to pyrimidine derivatives. Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine. As nucleotides in DNA and RNA, pyrimidine nucleotide derivatives have a wide range of biological applications. For example, pyrimidine derivatives are useful in DNA repair studies involving cancer and epigenetics.HPLC of Formula: 40230-24-8
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia