The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride(SMILESS: OC1=C(C)C(CO)=CN=C1C.[H]Cl,cas:148-51-6) is researched.Reference of 5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride. The article 《Convulsive seizure induced by intracerebral injection of semicarbazide (an anti-vitamin B6) in the mouse》 in relation to this compound, is published in Journal of Nutritional Science and Vitaminology. Let’s take a look at the latest research on this compound (cas:148-51-6).
Intracerebral injection of semicarbazide-HCl (I) [563-41-7] was more effective than systemic administration in inducing convulsions and tremors in mice. The symptoms were prevented by pyridoxine [65-23-6], aminooxyacetic acid [645-88-5] and acetone [67-64-1], but were enhanced by pyridoxal [66-72-8], pyridoxal phosphate [54-47-7] and other anti-B6 agents. Smaller doses of I were required for induction of the symptoms in vitamin B6-deficient mice than in controls. I applied to the vicinity of the lambda caused running fits, followed by convulsions and tremors.
Although many compounds look similar to this compound(148-51-6)Product Details of 148-51-6, numerous studies have shown that this compound(SMILES:OC1=C(C)C(CO)=CN=C1C.[H]Cl), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia