Let’s face it, organic chemistry can seem difficult to learn. Especially from a beginner’s point of view. Like 330786-24-8, Name is 3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine. In a document, author is Hamed, E. O., introducing its new discovery. HPLC of Formula: C17H13N5O.
Heterocyclization of Cyanoacetamide Derivatives: Synthesis and Biological Activity of Novel Azoles and Azines
The intermolecular cyclization of N-benzyl-2-cyanoacetamide with carbon disulfide followed by intramolecular cyclization gave thioxothiazinone 3. This compound was used to synthesize a series of novel fused furopyrrole, pyridine, pyrimidine and other azine and azole derivatives. The Michael-type reaction of compound 3 with maleic anhydride followed by pyrrole and furan cyclizations and aromatization yielded polycyclic compound 7. The [3+3]-cycloaddition of benzylidene malononitrile and its derivative to compound 3 gave pyridothiazines 10-12. The ring opening in compound 3 under the action of urea or thiourea followed by pyrimidine cyclization and subsequent air oxidation resulted in the synthesis of oxa- and thiadiazolopyrimidinones 15 and 16, respectively. The reaction of compound 3 with H2O2 in a basic medium provided pyrimidine derivative 17. The oxidation of compound 3 with Br-2 in an acid medium led to bromo derivative 19. The synthesized novel compounds were characterized by elemental analysis and IR and H-1 and C-13 NMR spectroscopy and tested antibacterial and anticancer activities.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 330786-24-8 help many people in the next few years. HPLC of Formula: C17H13N5O.
Reference:
Pyrimidine | C4H4N2 – PubChem,
,Pyrimidine – Wikipedia