Synthesis, antioxidant, and antiviral properties of pyrimidinylsulfamoyl azolyl acetamides was written by Divya, Kuppi Reddy Gari;Sowmya, Donthamsetty V.;Durgamma, Suram;Tharanath, Vadlamudi;Gopal, Divi Venkataramana Sai;Kumar, Malaka Venkateshwarulu Jyothi;Appa Rao, Chippada;Padmaja, Adivireddy;Padmavathi, Venkatapuram. And the article was included in Medicinal Chemistry Research in 2017.Recommanded Product: 40230-24-8 This article mentions the following:
A new class of pyrimidinylsulfamoyl azolyl acetamides was prepared from 2-pyrimidinylsulfamoyl acetic acid and 2-aminoazoles. The methoxy substituted pyrimidinylsulfamoyl oxazolyl acetamide (8e) displayed moderate antioxidant activity. The Me and methoxy substituted pyrimidinylsulfamoyl oxazolyl acetamides (8b, 8e) exhibited antiviral activity on BHK 21 cell lines with IC50 63.5, 44.5 μg/mL, resp. The compound 8e inhibited cytopathic changes induced by Blue Tongue Virus in cell lines. In the experiment, the researchers used many compounds, for example, 4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8Recommanded Product: 40230-24-8).
4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8) belongs to pyrimidine derivatives. Pyrimidine also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. For example, the neurotoxin tetrodotoxin is a pyrimidine derivative. It is found in a number of species including the Japanese puffer fish, the blue-ringed octopus, and the orange-bellied newt. Tetrodotoxin prevents the transmission of nerve signals and can result in paralysis and death.Recommanded Product: 40230-24-8
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia