In 2014,Dodonova, Jelena; Tumkevicius, Sigitas published 《Access to 6-arylpyrrolo[2,3-d]pyrimidines via a palladium-catalyzed direct C-H arylation reaction》.RSC Advances published the findings.Computed Properties of C6H3Cl2N3 The information in the text is summarized as follows:
An efficient method of palladium-catalyzed direct arylation has been developed for the selective functionalization of the C6 position of 2,4-diarylpyrrolo[2,3-d]pyrimidines I [R1 = Ph, 4-MeOC6H4, 4-(9-carbazolyl)phenyl]. Under optimal conditions, reactions with various aryl bromides R2Br [R2 = Ph, 4-NCC6H4, 4-PhC6H4, 4-(9-carbazolyl)phenyl, etc.] successfully provided a wide range of 6-arylpyrrolo[2,3-d]pyrimidines II.2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine(cas: 90213-66-4Computed Properties of C6H3Cl2N3) was used in this study.
2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine(cas: 90213-66-4) belongs to pyrimidine. Pyrimidine derivatives also play an important role in drug development, either in concert with other compounds or on their own. Computed Properties of C6H3Cl2N3They have been used in a wide variety of pharmaceuticals including general anesthetics, anti-epilepsy medication, anti-malaria medication, drugs for treating high blood pressure, and HIV medication.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia