Dolsak, Ana; Mrgole, Kristjan; Sova, Matej published the artcile< Microwave-assisted regioselective suzuki coupling of 2,4-dichloropyrimidines with aryl and heteroaryl boronic acids>, Application of C4H2Br2N2, the main research area is dihalopyrimidine boronic acid palladium regioselective Suzuki coupling microwave irradiation; halo arylpyrimidine preparation.
The Suzuki coupling of 2,4-dihalopyrimidines with aryl and heteroaryl boronic acids was investigated. A thorough screening of reaction conditions and the use of microwave irradiation leded to a very efficient and straightforward synthetic procedure provided arylpyrimidines in good to excellent yields. Short reaction time (15 min) and extremely low catalyst loading (0.5 mol%) were the main advantages of our tetrakis(triphenylphosphine)palladium(0) catalyzed microwave-assisted procedure, which could be used for quick and low-cost regioselective preparation of pyrimidine rings.
Catalysts published new progress about Arylboronic acids Role: RCT (Reactant), RACT (Reactant or Reagent). 3921-01-5 belongs to class pyrimidines, and the molecular formula is C4H2Br2N2, Application of C4H2Br2N2.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia