Related Products of 1159818-57-1, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1159818-57-1, name is 4-Amino-6-bromopyrimidine. This compound has unique chemical properties. The synthetic route is as follows.
A mixture of 6-bromopyrimidin-4-amine (1.01 g, 5.80 mmol) and ammonia solution (25 mL) was stirred in a sealed tube at 125 C overnight, then cooled down to rt and concentrated in vacuo. The residue was purified by silica gel column chromatography (MeOH/DCM (v/v) = 1/15) to give the title compound as a yellow solid (0.46 g, yield 72%).MS (ESI, pos. ion) m/z: 111.2 [M+H]+; (ppm): 7.82 (s, 1H), 6.10 (s, 4H), 5.39 (s, 1H).
According to the analysis of related databases, 1159818-57-1, the application of this compound in the production field has become more and more popular.
Reference:
Patent; SUNSHINE LAKE PHARMA CO., LTD.; CALITOR SCIENCES, LLC; XI, Ning; LI, Minxiong; PENG, Ju; LI, Xiaobo; ZHANG, Tao; HU, Haiyang; CHEN, Wuhong; BAI, Changlin; KE, Donghua; CHEN, Peng; (281 pag.)WO2019/99311; (2019); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia