Adding a certain compound to certain chemical reactions, such as: 4214-85-1, 2-Amino-6-methyl-5-nitro-3H-pyrimidin-4-one, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: 2-Amino-6-methyl-5-nitro-3H-pyrimidin-4-one, blongs to pyrimidines compound. Recommanded Product: 2-Amino-6-methyl-5-nitro-3H-pyrimidin-4-one
A mixture of 58 (20 g) with dry DMF (250 ml) and DMF dimethylacetal (75 ml) was stirred at 100 C. for 24 h and then cooled.. acetone (500 ml) was added and the mixture was filtered and washed with acetone affording 10 as an orange/brown solid (26.3 g, 80%).. Recrystallization from DMF gave an orange solid with mp>300 C. (dec).. 1H NMR (d6-DMSO) delta 8.59 (s, 1H), 7.81 (d, J=12.5 Hz, 1H), 5.30 (d, J=12.5 Hz, 1H), 3.12 (s, 3H), 3.00 (s, 3H), 2.93 (s, 6H).. 13C NMR delta 168.4, 166.0, 159.2, 158.5, 149.5, 129.1, 90.6, 41.8, 35.7.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,4214-85-1, 2-Amino-6-methyl-5-nitro-3H-pyrimidin-4-one, and friends who are interested can also refer to it.
Reference:
Patent; Industrial Research Limited; Albert Einstein College of Medicine of Yesheva University; US6693193; (2004); B1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia