Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 56843-79-9, name is 4-Chloro-2-methylthieno[2,3-d]pyrimidine. This compound has unique chemical properties. The synthetic route is as follows. SDS of cas: 56843-79-9
General procedure: The synthesis of target compound 2-11 (Scheme 1), commenced from commercially available ethyl-2-amino-3-thiophenecarboxylate (12a, Ri= H) and ethyl-2-amino-4,5-dimethyl-3- thiophenecarboxylate obtained using a reported method. Cyclization of 12a and 12b with HC1 (g) and acetonitrile gave 13a and 13b followed by chlorination with POCl3 afforded 14a and 14b respectively. Treatment with various substituted anilines in dioxane with 2 drops of cone HC1 provided 2-11. (60 -76 % yields).
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Reference:
Patent; DUQUESNE UNIVERSITY OF THE HOLY SPIRIT; GANGJEE, Aleem; (140 pag.)WO2017/31176; (2017); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia