Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 42754-96-1, name is 4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine. This compound has unique chemical properties. The synthetic route is as follows. HPLC of Formula: C5H2Cl2N4
Compound 4 (1.5 g, 7.9 mmol),Toluenesulfonic acid (752 mg, 3.96 mmol) was dissolved in THF (30 ml) and DCM (30 ml)Of the mixture,Further 3,4-dihydropyran (2 g, 23.7 mmol) was added,Stir at room temperature 22h,TLC detection (PE: EA = 20: 1),Raw material reaction is complete,Spin drying solvent,Column chromatography (PE: EA = 50: 1) afforded 5 (1.2 g) as a white solid,Yield 54.5%.
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Reference:
Patent; Sichuan Baili Pharmaceutical Co., Ltd.; Wu, Yong; Zhu, Yi; Hai, Li; Wang, Yiqian; Li, Jie; (22 pag.)(2016);,
Pyrimidine | C4H4N2 – PubChem,
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