Reference of 504-17-6, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 504-17-6, name is 4,6-Dihydroxy-2-mercaptopyrimidine, molecular formula is C4H4N2O2S, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
General procedure: A mixture of aldehyde (1 mmol), malanonitrile (1 mmol), barbituricor thiobarbituric acid (1 mmol), and DES (0.1 g, 36 mol%)was stirred in refluxing water (2 mL) for an appropriate period oftime. The reaction progress was followed by TLC (eluent: EtOAc: nhexane).After completion of the reaction, the mixture was dilutedwith water (4 mL) and filtered off. Finally, the solid product wasrecrystallized from warm ethanol if necessary.
According to the analysis of related databases, 504-17-6, the application of this compound in the production field has become more and more popular.
Reference:
Article; Biglari, Mohammad; Shirini, Farhad; Mahmoodi, Nosrat O.; Zabihzadeh, Mehdi; Mashhadinezhad, Maryam; Journal of Molecular Structure; vol. 1205; (2020);,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia