873-83-6, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 873-83-6, name is 6-Aminopyrimidine-2,4(1H,3H)-dione. This compound has unique chemical properties. The synthetic route is as follows.
Step 1: Synthesis of 7H-pyrrolo[2,3-d]pyrimidine-2,4-diol To a suspended solution of 6-aminouracil (12.7 g, 100 mmol) and sodium acetate (8.2 g, 100 mmol) in H2O (100 mL) at a temperature of 70-75¡ã C., was added a solution of chloroacetaldehyde (50percent in water, 23.6 g, 150 mmol). The resulting reaction mixture was stirred at 80¡ã C. for 20 min, and then cooled to room temperature. The separated solid was collected by filtration, washed with water and acetone, and dried in vacuum to give the title compound as brown solid (14.74 g, 98percent yield). MS(ESI, M-1) m/z 150.2.
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Reference:
Patent; Wyeth; US2010/3250; (2010); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia