Electric Literature of 933702-55-7, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 933702-55-7, name is 2-Chloropyrimidine-5-carbaldehyde, molecular formula is C5H3ClN2O, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
(3) Add 5.4 g (37.5 mmol) of 2-chloropyrimidin-5-formaldehyde, 5.0 g (31.2 mmol) of intermediate 2 and 30 ml of methanol to a 150 ml single-mouth bottle, stir and mix well, and add 0.4 g of ethylene to the mixture. The amine is heated to reflux 12, and the reaction is completed. After cooling the reaction product to room temperature, it was extracted with dichloromethane, washed with water, dried over anhydrous sodium sulfate, filtered, and evaporated.Dichloromethane was removed by distillation to give a crude material (yield: petroleum ether) to give the product 5-(2-chloropyrimidine-5-)methylene-4-phenylfuran-2 (5H) – Ketone 6.7 g, yield 62.8%.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 933702-55-7, 2-Chloropyrimidine-5-carbaldehyde.
Reference:
Patent; Yangtze University; Wu Qinglai; Cai Jinlong; (28 pag.)CN109761939; (2019); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia