Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Recommanded Product: 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide, 302964-08-5, Name is 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide, SMILES is CC1=CC=CC(Cl)=C1NC(=O)C1=CN=C(NC2=CC(Cl)=NC(C)=N2)S1, belongs to pyrimidines compound. In a document, author is Jadhav, Chetan K., introduce the new discover.
Room temperature ionic liquid promoted improved and rapid synthesis of highly functionalized imidazole and evaluation of their inhibitory activity against human cancer cells
In this study, we report the use of a 1,8-diazabicyclo [5.4.0]-undec-7-en-8-ium imidazolate ionic liquid as a catalyst as well as a green solvent for the expeditious multicomponent transformation of tetra- and trisubstituted imidazole scaffolds via four- and pseudo-four-component reactions with short reaction time, excellent yield, and purity of products. The ionic liquid is cheap, biodegradable, and can be recovered and reused for more than five consecutive cycles. The advantage of this protocol for gram-scale synthesis adds to its practical applicability. Selected synthesized tetra- and trisubstituted imidazole scaffolds were screened for their in vitro antiproliferative properties against the human cancer cell lines EC-109, MCF-7, HGC-27, and PC-3. Compounds 4m, 5e, and 5v showed potent cytotoxic activity against the human breast cancer cell line PC-3, MCF-7, and HGC-27, respectively.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 302964-08-5 is helpful to your research. Recommanded Product: 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide.
Reference:
Pyrimidine | C4H4N2 – PubChem,
,Pyrimidine – Wikipedia