Adding a certain compound to certain chemical reactions, such as: 73576-33-7, 4-Chloro-6-isopropylpyrimidin-2-amine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 73576-33-7, blongs to pyrimidines compound. Quality Control of 4-Chloro-6-isopropylpyrimidin-2-amine
General procedure: 2-Amino-4-chloro-6-isopropylpyrimidine (3, 1.0 mmol,171.6 mg) or 143.6 mg 2-amino-4-chloro-6-methylpyrimidine(4, 1 mmol), 62.8 mg iodoferrocene (1, 0.2 mmol),3.4 mg Pd(OAc)2 (0.01 mmol), 5.4 mg PPh3 (0.02 mmol),146 mm3 triethylamine (1.0 mmol), and 4 cm3 DMF weretransferred under an inert atmosphere into a stainless steelautoclave. It was charged with carbon monoxide (30 bar atroom temperature) and stirred at 100 C for 3 h. Theproducts were isolated by column chromatography (silica,eluent: n-hexane/EtOAc = 1/1).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,73576-33-7, its application will become more common.
Reference:
Article; Fehr, Csaba; Habu, Ivan; Wouters, Johan; Skoda-Foeldes, Rita; Monatshefte fur Chemie; vol. 145; 12; (2014); p. 1981 – 1986;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia