Synthetic Route of 1004-40-6, Adding some certain compound to certain chemical reactions, such as: 1004-40-6, name is 6-Amino-4-hydroxy-2-mercaptopyrimidine,molecular formula is C4H5N3OS, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1004-40-6.
Ethyl iodide (12 mmol) was added dropwise into a solutionof6-amino-2-thioxo-2,3-dihydropyrimidin-4(1H)-one(6mmol)in KOH (6.2 mmol) and then the reaction mixture was stirred atroom temperature overnight. The obtained solid was collectedby filtration, washed with petroleum ether, and then dried. The solid product was sufficiently pure to be used in the subsequentreactions without further purification. Yield: 85 %, white crys-tals (EtOH), mp 220-222 8 C (Lit.[41]218-219 8 C). n max /cm 13465 (NH), 3275-3260 (NH 2 ), 2926 (C-H aliphatic), 1659(C=O), 1571 (C=N stretching), 1453 (C=C stretching). dH(90 MHz, DMSO-d 6 ) 11.80 (s, 1H, NH(3)), 6.45 (s, 2H, NH 2 ),5.00 (s, 1H), 3.10 (q, J 18.0, 2H), 1.30 (t, J 18.0, 3H).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 1004-40-6, 6-Amino-4-hydroxy-2-mercaptopyrimidine, other downstream synthetic routes, hurry up and to see.
Reference:
Article; El-Mahdy, Ahmed F. M.; El-Sherief, Hassan A. H.; Hozien, Zainab A.; Australian Journal of Chemistry; vol. 72; 7; (2019); p. 542 – 554;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia