Extracurricular laboratory: Synthetic route of 125401-75-4

At the same time, in my other blogs, there are other synthetic methods of this type of compound,125401-75-4, 2,6-Bis((4,6-dimethoxypyrimidin-2-yl)oxy)benzoic acid, and friends who are interested can also refer to it.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 125401-75-4, name is 2,6-Bis((4,6-dimethoxypyrimidin-2-yl)oxy)benzoic acid. This compound has unique chemical properties. The synthetic route is as follows. 125401-75-4

4.3 g (10.0 mmol) of Intermediate 3 was dissolved in 60 mL of toluene, and 3.54 g(30.0 mmol) of thionyl chloride and the mixture was refluxed for 4.0 h. After cooling, toluene and excess thionyl chloride were distilled off under reduced pressure to giveIn the next step.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,125401-75-4, 2,6-Bis((4,6-dimethoxypyrimidin-2-yl)oxy)benzoic acid, and friends who are interested can also refer to it.

Reference:
Patent; Yang Zihui; Tian Hao; Yang Gongzhen; (6 pag.)CN107311982; (2017); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia