Renault, Sylviane; Renault, Jean; Cavier, Raymond published an article about the compound: 4-Chloro-8-methylquinoline( cas:18436-73-2,SMILESS:CC1=C2N=CC=C(Cl)C2=CC=C1 ).HPLC of Formula: 18436-73-2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:18436-73-2) through the article.
Alkylaminoquinolines I (n = 7-17; R = 2-Me, 2-Ph, H, 3-Me; R1 = H, S-Me, 6-Me, 7-Me, 8-Me, 8-Et, 8-CHMe2) were prepared by aminating 4-chloroquinolines. The amebicidal activity of I was maximum when n = 7-9. Methylation of the ring had little effect on amebicidal activity. Some of the chloroquinolines were prepared by treating anilines with EtOCH:C(CO2Et)2 or AcCH2CO2Et, cyclizing, decarboxylating the quinolinecarboxylates, and chlorinating the quinolinol.
This literature about this compound(18436-73-2)HPLC of Formula: 18436-73-2has given us a lot of inspiration, and I hope that the research on this compound(4-Chloro-8-methylquinoline) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia