Application of 1197953-49-3, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1197953-49-3, name is (2-((2,5-Dichloropyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide. This compound has unique chemical properties. The synthetic route is as follows.
171 mg of compound c25-12 and 165 mg of compound b3-1 were dissolved in 13 mL of ethylene glycol monomethyl ether and 0.43 mL of ethanol, and 0.26 mL of a hydrogen chloride solution (5.6 M) was added thereto, and the mixture was reacted at 120 C for 18 hours.The solvent was removed under reduced pressure, water was added to PH 9 with potassium carbonate, extracted with dichloromethane, dried, concentrated, obtained by column chromatography 24mg compound c-25;
According to the analysis of related databases, 1197953-49-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Zhejiang Tongyuankang Pharmaceutical Co., Ltd.; Wu Yusheng; Zhi Wubin; Wang Xin; Wu Shiyong; Li Jingya; Guo Ruiyun; Zheng Maolin; Liang Apeng; Wang Guohui; Chen Mingtao; Ma Jie; Niu Chengshan; (65 pag.)CN108689994; (2018); A;,
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