Adding a certain compound to certain chemical reactions, such as: 767-15-7, 2-Amino-4,6-dimethylpyrimidine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, SDS of cas: 767-15-7, blongs to pyrimidines compound. SDS of cas: 767-15-7
2-Chloromethyl-5,7-dimethyl-imidazo[1,2-a]pyrimidine A solution of 2-amino-4,6-dimethylpyrimidine (2.46 g, 20.0 mmol) and 1 ,3-dichloro-2- propanone (2.67 g, 21.0 mmol) in 1 ,2-dimethoxyethane (20 ml_) was stirred at 45 0C overnight. A precipitate formed, and this was collected by filtration, and was then refluxed with ethanol (15 ml_) for 2 hours. After cooling to room temperature, the product precipitated as white needles which were collected by filtration and vacuum dried to yield the title compound pure as its hydrochloride salt (883 mg, 19percent). 1H NMR (500 MHz, DMSO-de): delta7.84 (s, 1 H), 6.88 (s, 1 H), 4.84 (s, 2H), 2.60 (s, 3H), 2.49 (s, 3H).
At the same time, in my other blogs, there are other synthetic methods of this type of compound,767-15-7, 2-Amino-4,6-dimethylpyrimidine, and friends who are interested can also refer to it.
Reference:
Patent; H. Lundbeck A/S; WO2009/152825; (2009); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia