Electric Literature of 5399-92-8, Adding some certain compound to certain chemical reactions, such as: 5399-92-8, name is 4-Chloro-1H-pyrazolo[3,4-d]pyrimidine,molecular formula is C5H3ClN4, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 5399-92-8.
General procedure: 3-substituted-1H-pyrazolo[3,4-d]pyrimidine(10 mmol) was dissolved in DMF (15 mL).1-tert-butoxycarbonylpiperazine (10.5 mmol), microwave reaction at 90 C for 20-30 min, the reaction is completed, the reaction solution is quenched with ice water (150 mL).The organic phase was extracted with aq. EtOAc (3¡Á30 mL). In addition to solvents,Purification by column chromatography (petroleum ether: ethyl acetate = 1:3) gave Intermediate 2
According to the analysis of related databases, 5399-92-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Zunyi Medical College; Yang Dezhi; Wang Beilei; Yuan Zeli; Linghu Lang; (11 pag.)CN108752351; (2018); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia